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Biography and Research Information
OverviewAI-generated summary
Ana I. Coelho's research investigates molecular and physiological mechanisms underlying bone health and metabolic disorders. Her work includes studying the role of RANK ligand in osteoclast gene expression and examining the effects of aging on bone mechanoresponsiveness in mesenchymal lineage cells. Coelho has also explored the impact of exercise, such as long-term swimming, on bone quality in rat models, and investigated the association between adipose tissue distribution and bone quality in ovariectomized rats. Additionally, her research extends to genetic disorders, with publications on novel mRNA therapy for classic galactosemia, exploring its restoration of protein and enzyme activity in zebrafish models. Coelho has collaborated with researchers at the University of Arkansas for Medical Sciences, including Aaron Warren and Maria Almeida, on multiple publications.
Metrics
- h-index: 13
- Publications: 29
- Citations: 942
Selected Publications
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The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone (2025)
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Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025)
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Estrogens protect bone mass by inhibiting NAD <sup>+</sup> metabolism in osteoclasts (2025)
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The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)
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Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells (2025)
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Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness (2025)
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Differences In Femur And Lumbar Vertebra Adaptations To Running And Swimming In Wistar Rat Models (2024)
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RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression (2023)
Collaboration Network
Top Collaborators
Hélder Fonseca
Universidade do Porto (PT)
7 shared publications
- Mechanical loading prediction through accelerometry data during walking and running
- Association between Visceral and Bone Marrow Adipose Tissue and Bone Quality in Sedentary and Physically Active Ovariectomized Wistar Rats
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality
- Differences In Femur And Lumbar Vertebra Adaptations To Running And Swimming In Wistar Rat Models
- A Positive Impact Of Eight Months Swimming On Lumbar Vertebrae In Growing Rats
Showing 5 of 7 shared publications
Maria Almeida
University of Arkansas for Medical Sciences
7 shared publications
In database
- RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
Showing 5 of 7 shared publications
Aaron Warren
University of Arkansas for Medical Sciences
6 shared publications
In database
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- The adverse effects of chemotherapy on bone mass are not prevented by senolytics
Showing 5 of 6 shared publications
Andréa Bezerra
Universidade do Porto (PT)
5 shared publications
- Association between Visceral and Bone Marrow Adipose Tissue and Bone Quality in Sedentary and Physically Active Ovariectomized Wistar Rats
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality
- Differences In Femur And Lumbar Vertebra Adaptations To Running And Swimming In Wistar Rat Models
- A Positive Impact Of Eight Months Swimming On Lumbar Vertebrae In Growing Rats
- Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Ha‐Neui Kim
University of Arkansas for Medical Sciences
5 shared publications
In database
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Estrogens protect bone mass by inhibiting NAD <sup>+</sup> metabolism in osteoclasts
- Estrogens protect bone mass by inhibiting NAD <sup>+</sup> metabolism in osteoclasts
Laura Freitas
Universidade do Porto (PT)
4 shared publications
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality
- Differences In Femur And Lumbar Vertebra Adaptations To Running And Swimming In Wistar Rat Models
- A Positive Impact Of Eight Months Swimming On Lumbar Vertebrae In Growing Rats
- Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
María Gómez-Lázaro
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
4 shared publications
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality
- Differences In Femur And Lumbar Vertebra Adaptations To Running And Swimming In Wistar Rat Models
- A Positive Impact Of Eight Months Swimming On Lumbar Vertebrae In Growing Rats
- Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Md Mohsin Ali
University of Arkansas for Medical Sciences (US)
4 shared publications
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- The adverse effects of chemotherapy on bone mass are not prevented by senolytics
Leonardo Yung dos Santos Maciel
Universidade Federal de Sergipe (BR)
3 shared publications
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality
- Differences In Femur And Lumbar Vertebra Adaptations To Running And Swimming In Wistar Rat Models
- Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Tânia Amorim
University of Thessaly (GR)
3 shared publications
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality
- A Positive Impact Of Eight Months Swimming On Lumbar Vertebrae In Growing Rats
- Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Ricardo J. Fernandes
Universidade do Porto (PT)
3 shared publications
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality
- A Positive Impact Of Eight Months Swimming On Lumbar Vertebrae In Growing Rats
- Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Qiang Fu
University of Arkansas for Medical Sciences
3 shared publications
In database
- Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
Intawat Nookaew
University of Arkansas for Medical Sciences
3 shared publications
In database
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
Gareeballah Osman Adam
University of Arkansas for Medical Sciences (US)
3 shared publications
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- Estrogens protect bone mass by inhibiting NAD <sup>+</sup> metabolism in osteoclasts
Charles A. O’Brien
University of Arkansas for Medical Sciences
3 shared publications
In database
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
- The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone
- Mechanisms of mitochondrial reactive oxygen species action in bone mesenchymal cells
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