Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-09
R
Ruud P.M. Dings
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
High Impact
Associate Professor
Also affiliated: University of Minnesota (2002–2024); University of Arkansas Medical Center (2021–2026); Maastricht University Medical Centre (2003–2011); Maastricht University (2003–2011); Masonic Cancer Center (2011)
40 h-index
130 pubs
5,312 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ruud P.M. Dings' research focuses on cancer biology and treatment, with a particular emphasis on angiogenesis and its role in tumor growth. His work investigates how targeting tumor vasculature can be a therapeutic strategy. This includes studying specific inhibitors like Galectin-1 and examining the effects of combining anti-angiogenesis therapies with other treatments, such as radiation and metformin.
Dings has received funding from the NIH/National Cancer Institute for research aimed at improving cellular immunotherapy during dysbiosis. His publications also explore the molecular mechanisms underlying tumor angiogenesis, including the epigenetic regulation of endothelial cell anergy and the targeting of specific angiogenic vasculature in colon cancer. He has also investigated the potential of novel antitumor agents, such as calixarene 0118, as inhibitors of galectin-1.
With a career marked by significant scholarly output, Dings has an h-index of 40 and has authored over 128 publications, accumulating more than 5,307 citations. He actively collaborates with researchers at the University of Arkansas for Medical Sciences and the University of Arkansas at Fayetteville, including Samir V. Jenkins and Robert Griffin.
Metrics
- h-index: 40
- Publications: 130
- Citations: 5,312
Positions
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Associate Professor 2022–presentUniversity of Arkansas for Medical Sciences Radiation Oncology ORCID
Selected Publications
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Synthesis of Peptide Analogs From Fish Venom With Potential Antimicrobial and Anticancer Activity (2026)
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Abstract 4785: Thermal regulation of dysbiotic tumor vasculature (2026)
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Abstract 7625: Development of a blood-based tumor hypoxia detection assay (2026)
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Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026)
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Investigating Biomarkers of Radiation Resistance in Head and Neck Cancer Using Raman Spectroscopy (2025)
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CB-839 induces reversible dormancy in lung tumor-cells (2024)
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Bystander Effects in Spatially Fractionated Radiation Therapy: From Molecule To Organism To Clinical Implications (2024)
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Morphological Effects and In Vitro Biological Mechanisms of Radiation-Induced Cell Killing by Gold Nanomaterials (2023)
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Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
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Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking (2023)
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Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy (2022)
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Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis (2022)
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Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells (2021)
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Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces (2021)
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Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors (2021)
Federal Grants 1 $348,182 total
NIH
Contact PI
Sep 2021 - Aug 2027
Improvement of cellular immunotherapy during dysbiosis- Resubmission
Collaboration Network
Top Collaborators
Robert J. Griffin
Winthrop Rockefeller Foundation
29 shared publications
In database
- Galectins as Molecular Targets for Therapeutic Intervention
- Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Combination of Gold Nanoparticle-Conjugated Tumor Necrosis Factor-α and Radiation Therapy Results in a Synergistic Antitumor Response in Murine Carcinoma Models
Showing 5 of 29 shared publications
Samir V. Jenkins
University of Arkansas for Medical Sciences
24 shared publications
In database
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Sample storage conditions induce post-collection biases in microbiome profiles
Showing 5 of 24 shared publications
Kieng B. Vang
University of Arkansas at Little Rock (US)
13 shared publications
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Sample storage conditions induce post-collection biases in microbiome profiles
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Modifying Dendritic Cell Activation with Plasmonic Nano Vectors
- Targeting Artificial Tumor Stromal Targets for Molecular Imaging of Tumor Vascular Hypoxia
Showing 5 of 13 shared publications
Narasimhan Rajaram
University of Arkansas at Fayetteville
12 shared publications
In database
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells
- A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro
- Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance
- Spectroscopic investigation of radiation-induced reoxygenation in radiation-resistant tumors
Showing 5 of 12 shared publications
Azemat Jamshidi‐Parsian
Winthrop Rockefeller Foundation
7 shared publications
In database
- Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Combination of Gold Nanoparticle-Conjugated Tumor Necrosis Factor-α and Radiation Therapy Results in a Synergistic Antitumor Response in Murine Carcinoma Models
- Targeting Artificial Tumor Stromal Targets for Molecular Imaging of Tumor Vascular Hypoxia
- Enhanced Photothermal Treatment Efficacy and Normal Tissue Protection via Vascular Targeted Gold Nanocages
Showing 5 of 7 shared publications
Charles M. Quick
7 shared publications
In database
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Combination of Gold Nanoparticle-Conjugated Tumor Necrosis Factor-α and Radiation Therapy Results in a Synergistic Antitumor Response in Murine Carcinoma Models
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Real-time monitoring of circulating tumor cell (CTC) release after nanodrug or tumor radiotherapy using in vivo flow cytometry
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
Showing 5 of 7 shared publications
Kinan Alhallak
University of Arkansas at Fayetteville (US)
7 shared publications
- Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells
- A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro
- Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance
- Rapid quantification of mitochondrial fractal dimension in individual cells
- Abstract 1673: Optical metabolic imaging of response to radiation in radiation-sensitive and resistant lung cancer cells
Showing 5 of 7 shared publications
Eric R. Siegel
Winthrop Rockefeller Foundation
7 shared publications
In database
- Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Spectroscopic investigation of radiation-induced reoxygenation in radiation-resistant tumors
- CB-839 induces reversible dormancy in lung tumor-cells
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
Showing 5 of 7 shared publications
Dmitry A. Nedosekin
University of Arkansas for Medical Sciences
6 shared publications
In database
- Combination of Gold Nanoparticle-Conjugated Tumor Necrosis Factor-α and Radiation Therapy Results in a Synergistic Antitumor Response in Murine Carcinoma Models
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Modifying Dendritic Cell Activation with Plasmonic Nano Vectors
- Real-time monitoring of circulating tumor cell (CTC) release after nanodrug or tumor radiotherapy using in vivo flow cytometry
- Enhanced Photothermal Treatment Efficacy and Normal Tissue Protection via Vascular Targeted Gold Nanocages
Showing 5 of 6 shared publications
Alexandru S. Biris
University of Arkansas at Little Rock
5 shared publications
In database
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Modifying Dendritic Cell Activation with Plasmonic Nano Vectors
- Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells
- Dendritic cell biocompatibility of ether‐based urethane films
- Abstract LB-312: Breast cancer targeting by theranostic gold nanorods
Martin J. Cannon
University of Arkansas for Medical Sciences
5 shared publications
In database
- Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Design of Gold Nanoparticles in Dendritic Cell‐Based Vaccines
- Abstract 3529: T-cell trafficking and extravasation is suppressed in distal tumors during gastrointestinal tract dysbiosis
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
- Supplemental Figures 1-9 and Table S1 from Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
Nathan A. Koonce
National Center for Toxicological Research
4 shared publications
In database
- Combination of Gold Nanoparticle-Conjugated Tumor Necrosis Factor-α and Radiation Therapy Results in a Synergistic Antitumor Response in Murine Carcinoma Models
- Galectin-1 Inhibitor OTX008 Induces Tumor Vessel Normalization and Tumor Growth Inhibition in Human Head and Neck Squamous Cell Carcinoma Models
- Real-time monitoring of circulating tumor cell (CTC) release after nanodrug or tumor radiotherapy using in vivo flow cytometry
- Targeting Artificial Tumor Stromal Targets for Molecular Imaging of Tumor Vascular Hypoxia
Paola Monterroso Díaz
University of Arkansas at Fayetteville
4 shared publications
In database
- Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment
- Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance
- Quantitative Diffuse Optical Spectroscopy of Short-term Reoxygenation Kinetics in Radiation-Resistant and Sensitive Tumors
- Optical imaging and spectroscopy of microenvironmental changes associated with radiation resistance in tumors
Daria Semeniak
University of Arkansas for Medical Sciences (US)
4 shared publications
- Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance
- Determining the Sensitivity of Diffuse Reflectance Spectroscopy to Dose- and Depth-Dependent Changes in Tumor Oxygenation after Radiation Therapy
- Quantitative Diffuse Optical Spectroscopy of Short-term Reoxygenation Kinetics in Radiation-Resistant and Sensitive Tumors
- Optical imaging and spectroscopy of microenvironmental changes associated with radiation resistance in tumors
Zeid A. Nima
University of Arkansas at Little Rock
4 shared publications
In database
- Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
- Modifying Dendritic Cell Activation with Plasmonic Nano Vectors
- Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells
- Abstract LB-312: Breast cancer targeting by theranostic gold nanorods
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