Mackean P. Maisha

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Mathematical Statistician/Biostatistician

NCTR

Also affiliated: United States Food and Drug Administration (2014–2024); Center for Drug Evaluation and Research (2016)

7 h-index 12 pubs 240 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website

OverviewAI-generated summary

Mackean P. Maisha's research focuses on toxicological studies, particularly investigating the dose-response relationships and long-term effects of various chemical compounds in animal models and human patient samples. Recent work includes assessing the toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats and conducting inhalation toxicity studies of NNK, a nitrosamine, in the same rat model. Maisha also investigates genotoxicity by examining erythrocyte PIG-A mutant frequencies in cancer patients undergoing cisplatin treatment. Further research includes a two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice. Maisha has published 12 papers, accumulating 221 citations and an h-index of 7. Key collaborators include Robert P. Felton, Robert H. Heflich, Mason G. Pearce, and Ralph E. Patton, all from the National Center for Toxicological Research, with whom Maisha has co-authored multiple publications.

Metrics

h-index: 7
Publications: 12
Citations: 240

Positions

Mathematical Statistician/Biostatistician 2013–present

National Center for Toxicological Research/US FDA OSC/Division of Bioinformatics & Biostatistics ORCID
Biometric Consulting lab/Graduate Research Assisitant 2006–2010

University of North Carolina at Chapel Hill Gillings School of Global Public Health Biostatistics ORCID
Biostatistician 2001–2004

Harvard School of Public Health Center for Biostatistics in AIDS Research (CBAR) ORCID

Selected Publications

Erythrocyte PIG‐A mutant frequencies in cancer patients receiving cisplatin (2024)

Cancer Medicine 1 citation DOI OpenAlex
Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice (2023)

Archives of Toxicology 1 citation DOI OpenAlex
Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats (2022)

Toxicology Letters 23 citations DOI OpenAlex
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)

Food and Chemical Toxicology 6 citations DOI OpenAlex
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)

Toxicological Sciences 7 citations DOI OpenAlex
Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach (2019)

Journal of Proteome Research 31 citations DOI OpenAlex
A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results (2019)

Food and Chemical Toxicology 64 citations DOI OpenAlex
An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma (2019)

Journal of Proteome Research 27 citations DOI OpenAlex
An Aptamer‐Based Approach to Assess the Human Plasma Proteome for Pre‐Analytical Variability (2018)

The FASEB Journal DOI OpenAlex
In Vivo Monitoring of Sevoflurane-induced Adverse Effects in Neonatal Nonhuman Primates Using Small-animal Positron Emission Tomography (2016)

Anesthesiology 64 citations DOI OpenAlex
Positron Emission Tomography with [18F]FLT Revealed Sevoflurane-Induced Inhibition of Neural Progenitor Cell Expansion in vivo (2014)

Frontiers in Neurology 12 citations DOI OpenAlex