Mackean P. Maisha

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Mathematical Statistician/Biostatistician

NCTR

Also affiliated: American Institute of Certified Public Accountants (2016); United States Food and Drug Administration (2014–2021); Center for Drug Evaluation and Research (2016)

Faculty Researcher

7 h-index 12 pubs 236 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website

OverviewAI-generated summary

Mackean P. Maisha's research focuses on toxicological studies, particularly investigating the dose-response relationships and long-term effects of various chemical compounds in animal models and human patient samples. Recent work includes assessing the toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats and conducting inhalation toxicity studies of NNK, a nitrosamine, in the same rat model. Maisha also investigates genotoxicity by examining erythrocyte PIG-A mutant frequencies in cancer patients undergoing cisplatin treatment. Further research includes a two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice. Maisha has published 12 papers, accumulating 221 citations and an h-index of 7. Key collaborators include Robert P. Felton, Robert H. Heflich, Mason G. Pearce, and Ralph E. Patton, all from the National Center for Toxicological Research, with whom Maisha has co-authored multiple publications.

Metrics

h-index: 7
Publications: 12
Citations: 236

Selected Publications

Erythrocyte <i>PIG‐A</i> mutant frequencies in cancer patients receiving cisplatin (2024)

Cancer Medicine 1 citation DOI OpenAlex
Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice (2023)

Archives of Toxicology 1 citation DOI OpenAlex
Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats (2022)

Toxicology Letters 22 citations DOI OpenAlex
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)

Food and Chemical Toxicology 6 citations DOI OpenAlex
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)

Toxicological Sciences 7 citations DOI OpenAlex
Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach (2019)

Journal of Proteome Research 31 citations DOI OpenAlex
A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results (2019)

Food and Chemical Toxicology 62 citations DOI OpenAlex
An Integrated Analysis of Metabolites, Peptides, and Inflammation Biomarkers for Assessment of Preanalytical Variability of Human Plasma (2019)

Journal of Proteome Research 27 citations DOI OpenAlex
An Aptamer‐Based Approach to Assess the Human Plasma Proteome for Pre‐Analytical Variability (2018)

The FASEB Journal DOI OpenAlex
In Vivo Monitoring of Sevoflurane-induced Adverse Effects in Neonatal Nonhuman Primates Using Small-animal Positron Emission Tomography (2016)

Anesthesiology 64 citations DOI OpenAlex
Positron Emission Tomography with [18F]FLT Revealed Sevoflurane-Induced Inhibition of Neural Progenitor Cell Expansion in vivo (2014)

Frontiers in Neurology 12 citations DOI OpenAlex