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Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
T
Tonya M. Rafferty
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Also affiliated: University of Arkansas Medical Center (2025)
11 h-index
34 pubs
534 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Tonya M. Rafferty's research investigates the effects of ethanol on neuroinflammation and myelination in mouse models, particularly focusing on the cerebellum in postnatal models of fetal alcohol spectrum disorders. Her work also examines ethanol's impact on cerebellar and hippocampal neuroinflammation in chronic plus binge alcohol use models. Additionally, Rafferty has studied acetaminophen-induced hepatotoxicity in mice, including its effects on mitochondrial manganese superoxide dismutase and neuronal nitric-oxide synthase knockout mice. Her research has explored gene expression and DNA methylation changes following prenatal alcohol exposure, with an interest in the effects of methyl-supplemented diets. Rafferty has a publication record of 30 papers with 533 citations and an h-index of 11. She has collaborated extensively with Yunmeng Liu, Katherine Deck, and Christoph Mora, each with 15 shared publications.
Metrics
- h-index: 11
- Publications: 34
- Citations: 534
Selected Publications
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Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031 (2026)
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Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853 (2026)
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Kidney Resident Memory CD8+ T cells drive the immortality of hypertension (2026)
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Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension (2026)
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IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287 (2025)
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P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289 (2025)
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Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288 (2025)
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Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension (2025)
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Uncovering immune pathways for therapeutic targeting of hypertension (2025)
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Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)
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Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction (2025)
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Establishment of resident memory T cells anchors hypertension in the kidney (2025)
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T Cells Drive Kidney Memory for Hypertension (2024)
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Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024)
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P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION (2024)
Collaboration Network
Top Collaborators
Shengyu Mu
University of Arkansas for Medical Sciences
19 shared publications
In database
- CD8+ T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Uncovering immune pathways for therapeutic targeting of hypertension
Showing 5 of 19 shared publications
Katherine Deck
University of Arkansas for Medical Sciences
13 shared publications
In database
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Uncovering immune pathways for therapeutic targeting of hypertension
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
Showing 5 of 13 shared publications
Christoph Mora
University of Arkansas for Medical Sciences
13 shared publications
In database
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Uncovering immune pathways for therapeutic targeting of hypertension
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
Showing 5 of 13 shared publications
Shuoqiu Deng
University of Arkansas for Medical Sciences
12 shared publications
In database
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
Showing 5 of 12 shared publications
Yunmeng Liu
University of Arkansas for Medical Sciences
8 shared publications
In database
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- Establishment of resident memory T cells anchors hypertension in the kidney
Showing 5 of 8 shared publications
Pamela Rogers
University of Arkansas for Medical Sciences
8 shared publications
In database
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288
- IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
Showing 5 of 8 shared publications
Yunmeng Liu
University of Arkansas for Medical Sciences
7 shared publications
In database
- CD8+ T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Abstract 092: Novel Mechanism of Salt-sensitive Hypertension: CD8 + T Cells Stimulate Sodium Chloride Co-transporter NCC in Kidney
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- T Cells Drive Kidney Memory for Hypertension
Showing 5 of 7 shared publications
Cynthia J.M. Kane
University of Arkansas for Medical Sciences
7 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 7 shared publications
Paul D. Drew
University of Arkansas for Medical Sciences
7 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 7 shared publications
James C. Douglas
University of Arkansas for Medical Sciences
6 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 6 shared publications
Lance Benson
University of Arkansas for Medical Sciences (US)
5 shared publications
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Establishment of resident memory T cells anchors hypertension in the kidney
Yunping Guo
University of Arkansas for Medical Sciences
5 shared publications
In database
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
Victoria M. Niedzwiedz‐Massey
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
Kalee N. Holloway
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
- Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression
Pamela I. Rogers
University of Arkansas for Medical Sciences
4 shared publications
In database
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289
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