Match tier
Likely match
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
V
Vasily N. Dobrovolsky
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
High Impact
Researcher
Also affiliated: United States Food and Drug Administration (2004–2025); Institute of Bioorganic Chemistry (1993–1995); Diplomatic Academy of the Russian Foreign Ministry (2023); Food and Drug Administration (2008)
Faculty Researcher
29 h-index
105 pubs
2,574 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Vasily N. Dobrovolsky's research focuses on the detection and characterization of mutagenicity using advanced sequencing technologies. He has investigated the genome-wide detection of ultra-low-frequency substitution mutations resulting from exposure to chemical mutagens, employing methods such as PacBio and HiFi sequencing. His work includes evaluating the mutagenic effects of compounds like Molnupiravir and N4-hydroxycytidine in both bacterial and mammalian cells, as well as in vivo studies. Dobrovolsky has also explored the unbiased whole-genome detection of ultra-rare off-target mutations in genome-edited cell populations.
His research extends to the establishment of neural stem cells from fetal monkey brain for neurotoxicity testing. Dobrovolsky's publications also include studies on mutational signatures in T-lymphocytes of rats treated with specific chemical agents. He is a highly cited researcher with an h-index of 29 and over 2,500 citations across more than 100 publications. Key collaborators include Page B. McKinzie, Javier R. Revollo, Jaime A. Miranda, and Robert H. Heflich, all from the National Center for Toxicological Research.
Metrics
- h-index: 29
- Publications: 105
- Citations: 2,574
Selected Publications
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Using error-corrected sequencing for evaluating mutagenicity of molnupiravir in humans (2026)
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Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes (2025)
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Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment (2025)
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Erythrocyte <i>PIG‐A</i> mutant frequencies in cancer patients receiving cisplatin (2024)
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Whole-genome high-fidelity sequencing: A novel approach to detecting and characterization of mutagenicity in vivo (2023)
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Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by <scp>HiFi</scp> sequencing (2023)
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Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing (2023)
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Evaluation of the mutagenic effects of Molnupiravir and <scp>N4</scp>‐hydroxycytidine in bacterial and mammalian cells by <scp>HiFi</scp> sequencing (2022)
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Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing (2022)
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<scp>PacBio</scp> sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens (2021)
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Mutational signatures in T‐lymphocytes of rats treated with <i>N</i><scp>‐propyl‐</scp><i>N</i>‐nitrosourea and procarbazine (2021)
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<i>Pig‐a</i> gene mutations in bone marrow granulocytes of procarbazine‐treated <scp>F344</scp> rats (2021)
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Detection of Pig-a Mutant Erythrocytes in the Peripheral Blood of Rats and Mice (2020)
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Analysis of In Vivo Mutation in the Hprt and Tk Genes of Mouse Lymphocytes (2020)
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Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay (2020)
Collaboration Network
Top Collaborators
Page B. McKinzie
National Center for Toxicological Research
8 shared publications
In database
- Evaluation of the mutagenic effects of Molnupiravir and <scp>N4</scp>‐hydroxycytidine in bacterial and mammalian cells by <scp>HiFi</scp> sequencing
- Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing
- Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by <scp>HiFi</scp> sequencing
- Mutational signatures in T‐lymphocytes of rats treated with <i>N</i><scp>‐propyl‐</scp><i>N</i>‐nitrosourea and procarbazine
- Whole-genome high-fidelity sequencing: A novel approach to detecting and characterization of mutagenicity in vivo
Showing 5 of 8 shared publications
Javier R. Revollo
National Center for Toxicological Research
7 shared publications
In database
- Evaluation of the mutagenic effects of Molnupiravir and <scp>N4</scp>‐hydroxycytidine in bacterial and mammalian cells by <scp>HiFi</scp> sequencing
- <scp>PacBio</scp> sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens
- Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing
- Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by <scp>HiFi</scp> sequencing
- Mutational signatures in T‐lymphocytes of rats treated with <i>N</i><scp>‐propyl‐</scp><i>N</i>‐nitrosourea and procarbazine
Showing 5 of 7 shared publications
Jaime A. Miranda
United States Food and Drug Administration
4 shared publications
In database
- Evaluation of the mutagenic effects of Molnupiravir and <scp>N4</scp>‐hydroxycytidine in bacterial and mammalian cells by <scp>HiFi</scp> sequencing
- <scp>PacBio</scp> sequencing detects genome‐wide ultra‐low‐frequency substitution mutations resulting from exposure to chemical mutagens
- Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing
- Unbiased whole genome detection of ultrarare off‐target mutations in genome‐edited cell populations by <scp>HiFi</scp> sequencing
Mason G. Pearce
National Center for Toxicological Research
3 shared publications
In database
- Erythrocyte <i>PIG‐A</i> mutant frequencies in cancer patients receiving cisplatin
- <i>Pig‐a</i> gene mutations in bone marrow granulocytes of procarbazine‐treated <scp>F344</scp> rats
- Using error-corrected sequencing for evaluating mutagenicity of molnupiravir in humans
Robert H. Heflich
United States Food and Drug Administration
2 shared publications
In database
- Erythrocyte <i>PIG‐A</i> mutant frequencies in cancer patients receiving cisplatin
- <i>Pig‐a</i> gene mutations in bone marrow granulocytes of procarbazine‐treated <scp>F344</scp> rats
Timothy W. Robison
United States Food and Drug Administration (US)
2 shared publications
- Mutational signatures in T‐lymphocytes of rats treated with <i>N</i><scp>‐propyl‐</scp><i>N</i>‐nitrosourea and procarbazine
- Erythrocyte <i>PIG‐A</i> mutant frequencies in cancer patients receiving cisplatin
Azra Dad
National Center for Toxicological Research
1 shared publication
In database
- <i>Pig‐a</i> gene mutations in bone marrow granulocytes of procarbazine‐treated <scp>F344</scp> rats
Alexander W. Alund
National Center for Toxicological Research
1 shared publication
In database
- Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing
Jian Yan
United States Food and Drug Administration (US)
1 shared publication
- Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma <scp>L5178Y</scp> cells and <i>Caenorhabditis elegans</i> worms by <scp>PacBio</scp> sequencing
Leah E. Latham
National Center for Toxicological Research
1 shared publication
In database
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
Shuliang Liu
National Center for Toxicological Research
1 shared publication
In database
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
John Talpos
National Center for Toxicological Research
1 shared publication
In database
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
Joseph P. Hanig
United States Food and Drug Administration (US)
1 shared publication
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
William Slikker
National Center for Toxicological Research
1 shared publication
In database
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
Cheng Wang
National Center for Toxicological Research
1 shared publication
In database
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
Similar Researchers
Based on overlapping research topics
Page B. McKinzie
National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies
Molecular Biology Techniques and Applications
Genomics and Phylogenetic Studies
Robert H. Heflich
National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies
Molecular Biology Techniques and Applications
Genomics and Phylogenetic Studies
Javier R. Revollo
National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies
Molecular Biology Techniques and Applications
Genomics and Phylogenetic Studies
Meagan B. Myers
National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies
Molecular Biology Techniques and Applications
Genomics and Phylogenetic Studies
Binsheng Gong
National Center for Toxicological Research
Molecular Biology Techniques and Applications
Genomics and Phylogenetic Studies
Carcinogens and Genotoxicity Assessment
S A Montoya Guerrero
National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies
Molecular Biology Techniques and Applications
Carcinogens and Genotoxicity Assessment