Kevin D. Phelan
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor
Also affiliated: University of Freiburg (2011); Heidelberg University (2012); Universitätsklinikum des Saarlandes (2011); National Institute of Environmental Health Sciences (2011–2012); Environmental and Occupational Health Sciences Institute (1996); Gorgias Press (United States) (1996); Gibraltar Health Authority (2005); Institute of Neurobiology (2014); Health and Human Development (2HD) Research Network (2011); The University of Texas Medical Branch at Galveston (1989–1996); University of Pennsylvania (1992); Michigan State University (1982–1991); Saarland University (2011–2012)
Faculty Researcher
Neurobiology & Developmental Science, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Kevin D. Phelan is a professor in the Department of Neurobiology & Developmental Science at the University of Arkansas at Fayetteville. His research focuses on neurological disorders and treatments, particularly investigating the roles of ion channels in neuronal excitability and cell death. He has studied the canonical transient receptor potential (TRPC) channels, examining their contribution to hippocampal hyperexcitability and seizure-induced neuronal death, as well as their pharmacological differences in various neuronal populations.
Phelan's work also extends to neuroinflammation and metabolic pathways. He has investigated ethanol's modulation of cerebellar neuroinflammation in a mouse model of fetal alcohol spectrum disorders and explored the effects of liraglutide on endoplasmic reticulum stress in hypothalamic neurons. His research group has explored the localization of MC4R at synaptic sites of hypothalamic neurons. Phelan has secured federal funding for outreach programs aimed at exposing high school students to health and data science technologies, including the ArkanSONO program funded by the NIH/National Institute of General Medical Sciences for $266,590 and the AR Tech-DaSH program funded by the NIH/National Institute of Allergy and Infectious Diseases for $241,655.
With a career marked by active research, Phelan has published 86 works, accumulating over 2,350 citations and an h-index of 26. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Noor Akhter, Mohsin Syed, Fang Zheng, and U Thaung Shwe, on multiple publications.
Metrics
- h-index: 26
- Publications: 86
- Citations: 2,367
Selected Publications
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Ultrasonographic determination of bifurcation site of the tibial nerve at the tarsal tunnel (2025)
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MC4R Localizes at Excitatory Postsynaptic and Peri-Postsynaptic Sites of Hypothalamic Neurons in Primary Culture (2024)
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Investigating Contributions of Canonical Transient Receptor Potential Channel 3 to Hippocampal Hyperexcitability and Seizure-Induced Neuronal Cell Death (2024)
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Increased Susceptibility to Pilocarpine-Induced Status Epilepticus and Reduced Latency in TRPC1/4 Double Knockout Mice (2023)
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Improved Confidence and Clinical Application: The Effects of a Longitudinal Suture Curriculum for Medical Students (2023)
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Pharmacological Differences between Native Homomeric Transient Receptor Potential Canonical Type 4 Channels and Heteromeric Transient Receptor Potential Canonical Type 1/4 Channels in Lateral Septal Neurons (2023)
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Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology (2022)
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Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis (2022)
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Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology (2022)
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Retroaortic Left Renal Vein: An Incidental Finding During Cadaver Dissection (2022)
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Development of an Innovative Learning Model for Dietetic Interns Utilizing Gross Anatomy Lab Resources (2021)
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Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders (2021)
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Selective Survival of Sim1/MC4R Neurons in Diet-Induced Obesity (2020)
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Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum (2020)
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Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus (2020)
Federal Grants 2 $508,245 total
AR Tech-DaSH: Arkansas Technology and Data Science in Health and Medicine
ArkanSONO: A Technology Based Outreach Exposure Program for High School Students
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Lipid Stress and MC4R NIH Co-Investigator
- Dynamic neuroimmune interactions in the onset and progression of FASD NIH Co-Investigator
- MECHANISMS OF GABA-B INHIBITION AND EPILEPSY NIH Principal Investigator
- MHC CLASS I Expression and Function in Murine Cerebellum NIH/Nat. Inst. of Child Health & Human Development Principal Investigator
- Canonical Transient Receptor Potential Channels and Excitotoxicity NIH Co-Investigator
- METABOTROPIC GLUTAMATE RECEPTORS AND EXCITOTOXICITY NIH Co-Investigator
- The role of the endothelial NPYR1-TRPC3-ET1 signaling axis in neurovascular coupling dysfunction NIH Co-Investigator
- Microglia modulate ethanol impact on CNS development. NIH Co-Investigator
- Regulation of Neuroimmune Responses in FASD Models NIH Co-Investigator
- MHC CLASS I EXPRESSION AND FUNCTION IN MURINE CEREBELLUM NIH Principal Investigator
- Neuroinflammation: Role in FASD Cognitive Deficits NIH Co-Investigator
- ZINC-DEPENDENT APPARENT DESENSITIZATION OF NMDA RECEPTOR NIH Co-Investigator
Collaboration Network
Top Collaborators
- Retroaortic Left Renal Vein: An Incidental Finding During Cadaver Dissection
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Retroaortic Left Renal Vein: An Incidental Finding During Cadaver Dissection
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Pharmacological Differences between Native Homomeric Transient Receptor Potential Canonical Type 4 Channels and Heteromeric Transient Receptor Potential Canonical Type 1/4 Channels in Lateral Septal Neurons
- Investigating Contributions of Canonical Transient Receptor Potential Channel 3 to Hippocampal Hyperexcitability and Seizure-Induced Neuronal Cell Death
- Increased Susceptibility to Pilocarpine-Induced Status Epilepticus and Reduced Latency in TRPC1/4 Double Knockout Mice
- Pharmacological Differences between Native Homomeric Transient Receptor Potential Canonical Type 4 Channels and Heteromeric Transient Receptor Potential Canonical Type 1/4 Channels in Lateral Septal Neurons
- Investigating Contributions of Canonical Transient Receptor Potential Channel 3 to Hippocampal Hyperexcitability and Seizure-Induced Neuronal Cell Death
- Increased Susceptibility to Pilocarpine-Induced Status Epilepticus and Reduced Latency in TRPC1/4 Double Knockout Mice
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Bridging the Technology Divide in the COVID-19 Era: Using Virtual Outreach to Expose Middle and High School Students to Imaging Technology
- Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis
- MC4R Localizes at Excitatory Postsynaptic and Peri-Postsynaptic Sites of Hypothalamic Neurons in Primary Culture
- Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis
- MC4R Localizes at Excitatory Postsynaptic and Peri-Postsynaptic Sites of Hypothalamic Neurons in Primary Culture
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
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