L
Lauren Appell Institution-verified
Sourced from institutional research profiles (UAMS TRI or ARA).
Physician
faculty
2 h-index
15 pubs
15 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Lauren Appell's research focuses on pediatric hematology and oncology, with a particular interest in complex cases and treatment outcomes. Her work has explored the use of granulocyte infusions for children with severe neutropenia and fungal infections, and she has investigated the efficacy of CAR-T cell therapy for post-transplant lymphoproliferative disorders in pediatric heart transplant recipients. Appell has also studied inflammatory myositis as a late complication of hematopoietic stem cell transplantation (HSCT) in patients with primary immune deficiency disease. Additional research interests include central nervous system-symptomatic hyperammonemia following enzyme replacement therapy and the diagnosis of HHV-6 encephalitis after bone marrow transplantation. She has also been involved in studies evaluating exercise regimens for pediatric patients with acute lymphoblastic leukemia.
Metrics
- h-index: 2
- Publications: 15
- Citations: 15
Selected Publications
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Central nervous system-symptomatic hyperammonemia following recombinant crisantaspase Pseudomonas fluorescens (2026)
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A supervised STreNgth & Outpatient Exercise Regimen in pediatric patients with Acute Lymphoblastic Leukemia (STRONGER ALL) (2026)
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Liberalizing hospital proximity requirements for children/young adults with low-burden B-ALL receiving tisagenlecleucel (2025)
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130 A supervised strength and outpatient exercise regimen in pediatric patients with acute lymphoblastic leukemia (STRONGER ALL) (2025)
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Evaluation of recurrent and recalcitrant warts in a deaf adolescent male reveals GATA2 deficiency (2024)
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Inhibition of DNA-Pkcs As Novel Therapy for the Prevention of Acute Gvhd Following Hematopoietic Stem Cell Transplantation (2021)
Grants & Funding
Collaboration Network
Top Collaborators
Marie Burdine
University of Arkansas for Medical Sciences (US)
4 shared publications
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-Pkcs As Novel Therapy for the Prevention of Acute Gvhd Following Hematopoietic Stem Cell Transplantation
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
- DNA-PKcs is required for the activation and cytotoxicity of CD8+ effector T cells
Arunkumar Modi
University of Arkansas for Medical Sciences (US)
4 shared publications
- Inflammatory Myositis As Late Complication of HSCT in Primary Immune Deficiency Disease
- CAR-T for Pediatric Diffuse Large B-Cell Lymphoma Type Post-Transplant Lymphoproliferative Disorder in a Post Heart Transplant Patient
- Evaluation of recurrent and recalcitrant warts in a deaf adolescent male reveals GATA2 deficiency
- Improving Time to Antibiotic Administration with Initial Fever in HCT Recipients
Jason E. Farrar
University of Arkansas for Medical Sciences
4 shared publications
In database
- CAR-T for Pediatric Diffuse Large B-Cell Lymphoma Type Post-Transplant Lymphoproliferative Disorder in a Post Heart Transplant Patient
- Evaluation of recurrent and recalcitrant warts in a deaf adolescent male reveals GATA2 deficiency
- Acquired Hemophilia: A Rare Complication of Pediatric Idiopathic Multicentric Castleman Disease
- 130 A supervised strength and outpatient exercise regimen in pediatric patients with acute lymphoblastic leukemia (STRONGER ALL)
Ana Clara P. Azevedo‐Pouly
University of Arkansas for Medical Sciences
3 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
- DNA-PKcs is required for the activation and cytotoxicity of CD8+ effector T cells
Lyle Burdine
University of Arkansas for Medical Sciences (US)
3 shared publications
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
- DNA-PKcs is required for the activation and cytotoxicity of CD8+ effector T cells
Melanie Barker
Arkansas Children's Hospital
3 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
- DNA-PKcs is required for the activation and cytotoxicity of CD8+ effector T cells
Zachary J. Waldrip
Arkansas Children's Hospital (US)
3 shared publications
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
- DNA-PKcs is required for the activation and cytotoxicity of CD8+ effector T cells
Ms. Candace Mayle
Arkansas Children's Hospital (US)
3 shared publications
- Inflammatory Myositis As Late Complication of HSCT in Primary Immune Deficiency Disease
- CAR-T for Pediatric Diffuse Large B-Cell Lymphoma Type Post-Transplant Lymphoproliferative Disorder in a Post Heart Transplant Patient
- Improving Time to Antibiotic Administration with Initial Fever in HCT Recipients
Leslie Humiston
Arkansas Children's Hospital (US)
3 shared publications
- Inflammatory Myositis As Late Complication of HSCT in Primary Immune Deficiency Disease
- CAR-T for Pediatric Diffuse Large B-Cell Lymphoma Type Post-Transplant Lymphoproliferative Disorder in a Post Heart Transplant Patient
- Improving Time to Antibiotic Administration with Initial Fever in HCT Recipients
Lora J. Rogers
University of Arkansas for Medical Sciences
2 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
Lauren C. Morehead
University of Arkansas for Medical Sciences
2 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
Brian Koss
University of Arkansas for Medical Sciences
2 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 <sup>+</sup> helper and CD8 <sup>+</sup> effector T cells
Saumya Joshi
1 shared publication
- Inflammatory Myositis As Late Complication of HSCT in Primary Immune Deficiency Disease
Daniel Fil
University of Arkansas for Medical Sciences
1 shared publication
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
Randall R Rainwater
University of Arkansas for Medical Sciences
1 shared publication
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
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