Stepan Melnyk

High Impact

Professor

Last publication 2025 Last refreshed 2026-05-16

faculty

stepan.r.melnyk@lpnu.ua

55 h-index 175 pubs 10,927 cited

Biography and Research Information

OverviewAI-generated summary

Stepan Melnyk's research focuses on understanding the molecular mechanisms underlying various diseases, with a particular emphasis on oxidative stress, metabolic dysregulation, and their impact on neurodevelopment and cancer.

His work includes investigating the role of redox imbalance and methylation disturbances in early childhood obesity and examining associations between prenatal biomarkers of oxidative stress and Autism Spectrum Disorder (ASD)-related outcomes. Melnyk has also studied the protective effects of enhancer-activated RET against oxidative stress in acute myeloid leukemia and explored methods for inducing and assessing intestinal permeability in rodent models of radiation injury. He has conducted randomized controlled trials, such as one investigating sulforaphane and metabolite discovery in children with ASD, and analyzed the metabolic status of lean and obese Zucker rats using metabolomics.

Melnyk holds a distinguished record with an h-index of 55 and over 10,800 citations across 176 publications, recognizing him as a highly cited researcher. He collaborates with several researchers at the University of Arkansas for Medical Sciences, including Igor Koturbash, Reza Hakkak, Martin Hauer‐Jensen, and Rupak Pathak.

Metrics

  • h-index: 55
  • Publications: 175
  • Citations: 10,927

Selected Publications

  • Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice (2025)
  • The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months (2024)
    5 citations DOI OpenAlex
  • Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression (2022)
    8 citations DOI OpenAlex
  • Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder (2021)
    97 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

101 Collaborators 24 Institutions 4 Countries

Top Collaborators

View profile →
View profile →

Similar Researchers

Based on overlapping research topics