Stepan Melnyk
Professor
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Biography and Research Information
OverviewAI-generated summary
Stepan Melnyk's research focuses on understanding the molecular mechanisms underlying various diseases, with a particular emphasis on oxidative stress, metabolic dysregulation, and their impact on neurodevelopment and cancer.
His work includes investigating the role of redox imbalance and methylation disturbances in early childhood obesity and examining associations between prenatal biomarkers of oxidative stress and Autism Spectrum Disorder (ASD)-related outcomes. Melnyk has also studied the protective effects of enhancer-activated RET against oxidative stress in acute myeloid leukemia and explored methods for inducing and assessing intestinal permeability in rodent models of radiation injury. He has conducted randomized controlled trials, such as one investigating sulforaphane and metabolite discovery in children with ASD, and analyzed the metabolic status of lean and obese Zucker rats using metabolomics.
Melnyk holds a distinguished record with an h-index of 55 and over 10,800 citations across 176 publications, recognizing him as a highly cited researcher. He collaborates with several researchers at the University of Arkansas for Medical Sciences, including Igor Koturbash, Reza Hakkak, Martin Hauer‐Jensen, and Rupak Pathak.
Metrics
- h-index: 55
- Publications: 175
- Citations: 10,927
Selected Publications
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Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice (2025)
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The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months (2024)
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Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression (2022)
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Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder (2021)
Collaboration Network
Top Collaborators
- TRANSESTERIFICATION OF VEGETABLE OILS’ TRIGLYCERIDES BY THE HEAD FRACTION OF ETHYL ALCOHOL
- The assessment of sustainability indicators for triglycerides transesterification with alcohols catalyzed by ion exchange resins
- EFFECT OF PHYSICOCHEMICAL PROPERTIES OF d-METAL OXIDES ON SUNFLOWER OIL TRANSESTERIFICATION
- The regularities of aliphatic carboxylic acids and ethanolamines interaction
- TRANSESTERIFICATION OF TRIGLYCERIDES WITH PROPAN-2-OL CATALYSED BY SULFURIC ACID
Showing 5 of 20 shared publications
- TRANSESTERIFICATION OF VEGETABLE OILS’ TRIGLYCERIDES BY THE HEAD FRACTION OF ETHYL ALCOHOL
- The assessment of sustainability indicators for triglycerides transesterification with alcohols catalyzed by ion exchange resins
- EFFECT OF PHYSICOCHEMICAL PROPERTIES OF d-METAL OXIDES ON SUNFLOWER OIL TRANSESTERIFICATION
- TRANSESTERIFICATION OF TRIGLYCERIDES WITH PROPAN-2-OL CATALYSED BY SULFURIC ACID
- Transesterification of vegetable oil by ethanol in the presence of heterogeneous catalysts
Showing 5 of 8 shared publications
- Triglycerides Transesterification on Zeolites Modified with Bivalent Metal Ions
- Oleic Acid Adsorption on Ion Exchange Resin KU-2-8
- Triglycerides Transesterification on Zeolites Modified with Bivalent Metal Ions
- Oleic Acid Adsorption on Ion Exchange Resin KU-2-8
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Metabolic Status of Lean and Obese Zucker Rats Based on Untargeted and Targeted Metabolomics Analysis of Serum
- Abstract 740: Obesity promotes liver pro-oxidative and DNA damage in mammary tumor of Zucker rats
- Abstract 759: Soy protein diet changes metabolic profile in liver of 7,12-dimethylbenz(<i>α</i>)anthracene (DMBA)-induced mammary tumors in obese zucker rats
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells
- Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice
- The regularities of aliphatic carboxylic acids and ethanolamines interaction
- THE CATALYSTS IMPACT ON THE TRI- AND DIETHANOLAMINE AND ETHYL OLEATE INTERACTION
- The interaction regularities of acetic and oleic acids esters and triethanolamine
- TRANSESTERIFICATION OF TRIGLYCERIDES BY ALIPHATIC ALCOHOLS ON ZEOLITES
- Triglycerides Transesterification on Zeolites Modified with Bivalent Metal Ions
- Triglycerides Transesterification on Zeolites Modified with Bivalent Metal Ions
- Adsorption of oleic acid on AV-17-8 anion exchange resin
- Oleic Acid Adsorption on Ion Exchange Resin KU-2-8
- Oleic Acid Adsorption on Ion Exchange Resin KU-2-8
- Liquefaction of rye mash using SHEARZYME 500L enzyme preparation
- Transesterification of sunflower oil’s triglycerides by aliphatic alcohols С1–С4
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice
- The regularities of aliphatic carboxylic acids and ethanolamines interaction
- The interaction regularities of acetic and oleic acids esters and triethanolamine
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
- Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression
- The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months
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