Xuan Zhang Data-verified

OverviewAI-generated summary

Xuan Zhang's research focuses on the pharmacological effects and toxicity of various compounds, with an emphasis on their mechanisms of action and potential therapeutic applications. Zhang has investigated compounds such as cepharanthine, 1,8-cineole, escin, neferine, evodiamine, and rutecarpine, examining their impacts on conditions including lung adenocarcinoma, heart failure, depressive-like behavior, and cardiomyocyte injury. This work often involves studying signaling pathways, such as SIRT1/Nrf2/HO-1 and BDNF/TrkB/CREB, and the role of oxidative and endoplasmic reticulum stress.

Zhang's research also extends to analytical chemistry, specifically the rapid screening of pesticide residues in agricultural products like chrysanthemum flowers using advanced mass spectrometry techniques. Furthermore, Zhang has contributed to meta-analyses, including a study-level and patient-level meta-analysis on biologic TNF-α inhibitors for severe skin reactions like Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Zhang leads a research group and has collaborated with researchers at the National Center for Toxicological Research, including Fang Liu, Tucker A. Patterson, John Talpos, and Leah E. Latham, with several shared publications.

Metrics

• h-index: 25
• Publications: 80
• Citations: 2,236