Laura Ewing
Staff Fellow
Also affiliated: Center for Food Safety and Applied Nutrition (2013–2022); Center for Veterinary Medicine (2015); United States Food and Drug Administration (2012–2022); Children's Hospital of Philadelphia (2020); Food and Drug Administration (2015–2017); University of Pennsylvania (2020)
Staff Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Laura Ewing's research investigates the toxicological and pharmacological effects of cannabis and its extracts, particularly focusing on cannabidiol (CBD). Her work utilizes various animal models, including mice and rabbits, to study these effects. Recent publications by Ewing and collaborators examine the impacts of proton and oxygen ion irradiation on cardiovascular function in rabbits and explore methods for assessing intestinal permeability in rodent models following radiation injury. She also employs comparative genomic analyses and zebrafish infectivity studies to characterize microbial strains, such as Cronobacter sakazakii and Salmonella enterica, originating from food sources. Ewing's research network includes key collaborators from the University of Arkansas for Medical Sciences, such as Igor Koturbash, Charles M. Skinner, Martin Hauer‐Jensen, and Rupak Pathak, with whom she has co-authored multiple publications. Her scholarship metrics include an h-index of 17 with 60 total publications and 995 total citations.
Metrics
- h-index: 17
- Publications: 60
- Citations: 1,032
Selected Publications
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Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)
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Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024)
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Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese (2022)
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Methods for induction and assessment of intestinal permeability in rodent models of radiation injury (2022)
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Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration (2020)
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Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation (2020)
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Green Tea Extract as a Safe and Effective Dietary Supplement: Lessons Learned from Mice (2020)
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Cannabidiol: From Drug Interaction Potential to Modulation of the Gut Microbiome (2020)
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Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract (2020)
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The Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine Abuse (2020)
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Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome (2020)
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The development and characterization of an scFv-Fc fusion based gene therapy to reduce the psychostimulant effects of methamphetamine abuse (2019)
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Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration (2019)
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Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model (2019)
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Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice (2019)
Collaboration Network
Top Collaborators
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Methods for induction and assessment of intestinal permeability in rodent models of radiation injury
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
- Cytogenetic and epigenetic aberrations in peripheral lymphocytes of northwest Arkansas Marshallese
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