Biography and Research Information
OverviewAI-generated summary
Kirsten Clement's research investigates the toxicological and pharmacological effects of cannabis and its components, particularly cannabidiol (CBD), in various biological systems. Her work has utilized animal models, specifically inbred C57BL mice, and advanced in vitro systems such as human quad liver-on-chip models to bridge the gap between animal and human responses in toxicology studies. Clement has explored inter-strain variability in mouse responses to CBD-rich cannabis extracts and examined the role of compounds like methylsulfonylmethane in DNA methylation within human liver cells. Additionally, her research has extended to studying the long-term effects of simulated microgravity and galactic cosmic radiation on mouse lungs, focusing on sex-specific epigenetic reprogramming. She has published four papers, with recent work appearing in 2024 and 2025, and has collaborated with several researchers at the University of Arkansas for Medical Sciences, including Igor Koturbash, Mitchell R. McGill, Charles M. Quick, and Eric U. Yee.
Metrics
- h-index: 2
- Publications: 4
- Citations: 6
Selected Publications
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Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming (2025)
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Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)
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Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024)
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Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells (2022)
Collaboration Network
Top Collaborators
Igor Koturbash
4 shared publications
In database
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming
- Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells
David Williams
University of Arkansas for Medical Sciences (US)
3 shared publications
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming
Mitchell R. McGill
University of Arkansas for Medical Sciences
2 shared publications
In database
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells
Laura Ewing
University of Arkansas for Medical Sciences
2 shared publications
In database
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Charles M. Skinner
University of Arkansas for Medical Sciences
2 shared publications
In database
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Charles M. Quick
University of Arkansas for Medical Sciences
2 shared publications
In database
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Eric U. Yee
University of Arkansas for Medical Sciences
2 shared publications
In database
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Larry Walker
ElSohly Laboratories (United States) (US)
2 shared publications
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Mahmoud A. ElSohly
ElSohly Laboratories (United States) (US)
2 shared publications
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Bill J. Gurley
Office of Dietary Supplements (US)
2 shared publications
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Isabelle R. Miousse
University of Arkansas for Medical Sciences
1 shared publication
In database
- Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells
Sean G. Young
University of Arkansas for Medical Sciences (US)
1 shared publication
- Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells
Stepan Melnyk
Arkansas Children's Hospital
1 shared publication
In database
- Methylsulfonylmethane Serves as a Donor of Methyl Groups for Methylation of DNA in Human Liver HepaRG Cells
Ryan J. Harpenau
University of Arkansas for Medical Sciences
1 shared publication
In database
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
Stefanie Kennon‐McGill
University of Arkansas for Medical Sciences
1 shared publication
In database
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
Similar Researchers
Based on overlapping research topics
Charles M. Skinner
University of Arkansas for Medical Sciences
Cannabis and Cannabinoid Research
Drug-Induced Hepatotoxicity and Protection
Epigenetics and DNA Methylation
Jerry W. King
University of Arkansas at Fayetteville
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Marcelo Bigarella
University of Arkansas for Medical Sciences
Drug-Induced Hepatotoxicity and Protection
Epigenetics and DNA Methylation
Joseph DeLuca
University of Arkansas for Medical Sciences
Cannabis and Cannabinoid Research
Drug-Induced Hepatotoxicity and Protection
Stefanie Kennon‐McGill
University of Arkansas for Medical Sciences
Cannabis and Cannabinoid Research
Drug-Induced Hepatotoxicity and Protection
Qiangen Wu
National Center for Toxicological Research
Cannabis and Cannabinoid Research
Drug-Induced Hepatotoxicity and Protection