Bill J. Gurley
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Principal Scientist
Formerly Arkansas Affiliated with Arkansas State University, NCTR, University of Arkansas, UAMS through 2024; recent publications list United States Pharmacopeial Convention, University of Mississippi.
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Bill J. Gurley's research focuses on the complex interactions between dietary supplements, herbal products, and pharmaceutical drugs, particularly concerning their impact on human health and drug metabolism. He investigates how plant extracts and their constituents can modulate the activity of key drug-metabolizing enzymes, transporters, and nuclear receptors, which are critical for the safe and effective use of medications. His work also addresses the potential for hepatotoxicity arising from herbal dietary supplements and explores analytical challenges in ensuring the quality and safety of these products.
Gurley has published extensively on these topics, with recent work examining the modulatory effects of specific botanicals like Bulbine natalensis and Zingiber officinale on drug metabolism pathways. He also explores the broader landscape of herb-drug interactions for commonly used botanicals on the US market. His research network includes collaborators such as Igor Koturbash, Mitchell R. McGill, Charles M. Quick, and Eric U. Yee, all at the University of Arkansas for Medical Sciences, with whom he has co-authored multiple publications. Gurley's scholarship is evidenced by an h-index of 35 and over 5,900 citations across 171 publications.
Metrics
- h-index: 35
- Publications: 171
- Citations: 5,913
Selected Publications
-
Phenibut: A drug with one too many “buts” (2024)
-
Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)
-
Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024)
-
Pharmacokinetics (2023)
-
Hepatotoxicity due to herbal dietary supplements: Past, present and the future (2022)
-
Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration (2020)
-
Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract (2020)
-
Effect of Aromatase Inhibition (Exemestane) on Urine Concentration of Osteoprotegerin in Healthy Postmenopausal Women (2019)
-
The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications (2019)
-
Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration (2019)
-
Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model (2019)
-
Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice (2019)
-
Impact of obesity on the toxicity of a multi-ingredient dietary supplement, OxyELITE Pro™ (New Formula), using the novel NZO/HILtJ obese mouse model: Physiological and mechanistic assessments (2018)
Collaboration Network
Top Collaborators
- Hepatotoxicity due to herbal dietary supplements: Past, present and the future
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Phenibut: A drug with one too many “buts”
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Hepatotoxicity due to herbal dietary supplements: Past, present and the future
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- A Framework for Developing Intake and Use Guidance for Dietary Supplement Bioactives
- A Framework for Developing Intake and Use Guidance for Dietary Supplement Bioactives
- A Framework for Developing Intake and Use Guidance for Dietary Supplement Bioactives
Similar Researchers
Based on overlapping research topics