Yingni Che

OverviewAI-generated summary

Yingni Che's research focuses on the molecular mechanisms underlying cellular dysfunction, particularly in the context of inflammation and neuroinflammation. Her work investigates how microbial components, such as lipopolysaccharide (LPS) from Porphyromonas gingivalis, can trigger mitochondrial dysfunction and oxidative stress, leading to neuroinflammatory responses. Che also studies the role of sirtuin 1 (SIRT1) isoforms in regulating mitochondrial gene expression and function within muscle cells, and how inhibitors targeting the Rho/SRF pathway can modulate these mitochondrial processes. Her publications include investigations into how LPS-induced neuroinflammation impacts mitochondrial health through oxidative stress and how Rho/SRF inhibitors influence mitochondrial functions. Che has co-authored publications with researchers including Pankaj Patyal, Gohar M. Azhar, and Ambika Verma at the University of Arkansas for Medical Sciences. Her scholarly output includes 3 publications with an h-index of 2 and 59 total citations.

Metrics

• h-index: 2
• Publications: 3
• Citations: 59