Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
Biography and Research Information
OverviewAI-generated summary
Katherine Cruse's research focuses on the intersection of molecular biology and immunotherapy, specifically investigating how to enhance the efficacy of CAR-T cell therapy. Her recent work explores manipulating the DNA damage response to combat T cell exhaustion, a key limitation in achieving durable responses to immunotherapy. Cruse also studies the donor-intrinsic proteomic programs that influence CAR-T cell persistence, examining the molecular mechanisms that govern their long-term survival and anti-cancer activity. These investigations are conducted in collaboration with researchers at the University of Arkansas for Medical Sciences, including Brian Koss, Jessica L. Kelliher, Daniel Fil, and Lora J. Rogers, with whom she shares multiple publications.
Metrics
- Publications: 1
Selected Publications
-
236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response (2025)
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392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay (2025)
Collaboration Network
Top Collaborators
Lora J. Rogers
University of Arkansas for Medical Sciences
2 shared publications
In database
- 392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Daniel Fil
University of Arkansas for Medical Sciences
2 shared publications
In database
- 392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Sydnye L. Shuttleworth
University of Arkansas for Medical Sciences
2 shared publications
In database
- 392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Brian Koss
University of Arkansas for Medical Sciences
2 shared publications
In database
- 392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Jessica L. Kelliher
University of Arkansas for Medical Sciences
1 shared publication
In database
- 392 Donor-intrinsic proteomic programs shape CAR-T cell persistence across a longitudinal killing assay
Jessica L Kelliher
University of Arkansas for Medical Sciences
1 shared publication
In database
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Mousumi Patra
University of Arkansas for Medical Sciences
1 shared publication
In database
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
T Wonder NO Meridia
University of Arkansas for Medical Sciences
1 shared publication
In database
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Michael Bauer
University of Arkansas for Medical Sciences
1 shared publication
In database
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Katherine Wallis
University of Arkansas for Medical Sciences
1 shared publication
In database
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Thomas A. Williams
University of Central Arkansas
1 shared publication
In database
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Fen Xia
University of Arkansas for Medical Sciences
1 shared publication
In database
- 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response
Similar Researchers
Based on overlapping research topics
Brian Koss
University of Arkansas for Medical Sciences
CAR-T cell therapy research
Immune Response and Inflammation
Cancer-related molecular mechanisms research
Eva Allen
University of Arkansas for Medical Sciences
CAR-T cell therapy research
Immune Response and Inflammation
Cancer-related molecular mechanisms research
A. Edwards
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
DNA Repair Mechanisms
Protein Structure and Dynamics
Robert L. Eoff
University of Arkansas for Medical Sciences
Cancer-related molecular mechanisms research
DNA Repair Mechanisms
Protein Structure and Dynamics
Maroof K. Zafar
University of Arkansas for Medical Sciences
Immune Response and Inflammation
Cancer-related molecular mechanisms research
DNA Repair Mechanisms
Kaitlin Hicks
University of Arkansas for Medical Sciences
Immune Response and Inflammation
DNA Repair Mechanisms
Disease Models, Animal