Pieter J Koopmans Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Graduate Research Assistant

University of Arkansas at Fayetteville

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2 h-index 6 pubs 24 cited

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Biography and Research Information

OverviewAI-generated summary

Research by Pieter J Koopmans focuses on the molecular adaptations of skeletal muscle, particularly in response to exercise and aging. His work investigates the role of microRNAs (miRNAs) in regulating gene expression within adult skeletal muscle satellite cells, examining specific miRNAs like miR-16. Koopmans also studies the impact of myonuclei on exercise-induced molecular changes and explores the potential of senolytic compounds, such as BI01, to influence epigenetic markers and the methylome in aged and regenerating muscle tissue. His research extends to understanding the molecular mechanisms behind muscle wasting, as demonstrated by his investigation into cancer-induced muscle loss and the effects of mitochondrial antioxidants. Koopmans collaborates with several researchers at the University of Arkansas at Fayetteville, including Kevin A. Murach, Francielly Morena da Silva, Nicholas P. Greene, and Sabin Khadgi.

Metrics

  • h-index: 2
  • Publications: 6
  • Citations: 24

Selected Publications

  • Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle (2025) DOI
  • The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus (2025) DOI
  • Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle (2025) DOI
  • Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females (2025) DOI
  • Corrigendum to “microRNA-1 regulates metabolic flexibility by programming skeletal muscle pyruvate metabolism” [Mol Metabol 98 (2025) 1–23/102182] (2025) DOI
  • microRNA-1 regulates metabolic flexibility by programming adult skeletal muscle pyruvate metabolism (2025) DOI
  • Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice (2025) DOI
  • Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice (2025) DOI
  • At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic ( <scp>BI01</scp> ) Administration on <scp>DNA</scp> Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle (2025) DOI
  • The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth (2024) DOI
  • Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice (2024) DOI
  • microRNA-1 Regulates Metabolic Flexibility in Skeletal Muscle via Pyruvate Metabolism (2024) DOI
  • The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates <i>MYC</i> as a Hypertrophic Regulator That is Sufficient for Growth (2024) DOI
  • Stuart has got the PoWeR! Skeletal muscle adaptations to a novel heavy progressive weighted wheel running exercise model in C57BL/6 mice (2023) DOI
  • The roles of miRNAs in adult skeletal muscle satellite cells (2023) DOI

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