Wesley S. Haynie
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Researcher
Faculty Researcher
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Wesley S. Haynie's research investigates the biological mechanisms underlying skeletal muscle atrophy and regeneration, with a particular focus on sex-based differences in these processes. His work has explored the development of cachexia in both male and female mice, examining metabolic and contractile alterations, as well as the progression of skeletal muscle fibrosis in rodent models. Haynie has also studied mitochondrial aberrations during disuse atrophy and the effects of interventions such as voluntary wheel running on muscle recovery following volumetric muscle loss. His publications include investigations into the impact of PGC-1α overexpression on skeletal muscle regeneration and the influence of diet-induced obesity on extracellular matrix remodeling. Haynie has a publication record of 38 papers, with an h-index of 13 and 729 citations. He has collaborated extensively with researchers at the University of Arkansas at Fayetteville, including Tyrone A. Washington, Megan E. Rosa‐Caldwell, Nicholas P. Greene, and Eleanor R. Schrems.
Metrics
- h-index: 13
- Publications: 38
- Citations: 766
Selected Publications
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Leucine Supplementation Exacerbates Morbidity in Male but Not Female Mice with Colorectal Cancer-Induced Cachexia (2023)
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Development of skeletal muscle fibrosis in a rodent model of cancer cachexia (2023)
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Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia (2023)
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Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration (2022)
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Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice (2021)
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Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice (2021)
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Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy (2021)
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The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss (2021)
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The effect of diet-induced obesity on extracellular matrix remodeling during skeletal muscle regeneration (2021)
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Moderators of skeletal muscle maintenance are compromised in sarcopenic obese mice (2020)
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Comparative plasma proteomics in muscle atrophy during cancer‐cachexia and disuse: The search for atrokines (2020)
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Altering aspects of mitochondrial quality to improve musculoskeletal outcomes in disuse atrophy (2020)
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Cancer‐induced cardiac atrophy adversely affects myocardial redox state and mitochondrial oxidative characteristics (2020)
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Leucine Supplementation Exacerbates Atrophy In Cancer Cachectic Mice (2020)
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OXIDATIVE METABOLISM DURING THE TIME-COURSE OF DISUSE ATROPHY IN MALE AND FEMALE MICE (2020)
Collaboration Network
Top Collaborators
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
Showing 5 of 9 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- The effect of diet-induced obesity on extracellular matrix remodeling during skeletal muscle regeneration
Showing 5 of 8 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
Showing 5 of 8 shared publications
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- The effect of diet-induced obesity on extracellular matrix remodeling during skeletal muscle regeneration
- Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration
- Leucine Supplementation Exacerbates Morbidity in Male but Not Female Mice with Colorectal Cancer-Induced Cachexia
Showing 5 of 6 shared publications
- The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- The effect of diet-induced obesity on extracellular matrix remodeling during skeletal muscle regeneration
- Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration
- Leucine Supplementation Exacerbates Morbidity in Male but Not Female Mice with Colorectal Cancer-Induced Cachexia
Showing 5 of 6 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- The effect of diet-induced obesity on extracellular matrix remodeling during skeletal muscle regeneration
- Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The effect of diet-induced obesity on extracellular matrix remodeling during skeletal muscle regeneration
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Leucine Supplementation Exacerbates Morbidity in Male but Not Female Mice with Colorectal Cancer-Induced Cachexia
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
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