Match tier
Likely match
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-10-09
S
Seongkyun Lim
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Research Assistant
Also affiliated: University of California, Los Angeles (2023); East Carolina University (2018); Korea Institute of Oriental Medicine (2023)
13 h-index
41 pubs
494 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Seongkyun Lim's research focuses on understanding the molecular mechanisms underlying skeletal muscle adaptation and disease, particularly in the context of aging, exercise, and cancer cachexia.
Lim has investigated gene expression patterns and regulatory networks associated with acute skeletal muscle growth and exercise adaptation in aging. This work includes analyzing global and MYC-regulated networks and identifying molecular signatures that define exercise adaptation. Research also delves into the development and progression of cancer cachexia, a complex metabolic syndrome associated with cancer. Studies have examined the differences in catabolic signaling and transcriptional disruptions between male and female mice during cachexia and disuse atrophy, highlighting potential sex-based variations in disease progression. Further investigations explore mitochondrial aberrations and their differential effects on male and female mice during disuse atrophy.
Lim's work is supported by two NSF grants totaling $775,000, focused on the dynamic modeling of river ecosystem stability. Collaborations with researchers at the University of Arkansas at Fayetteville, including Francielly Morena da Silva, Tyrone A. Washington, Nicholas P. Greene, and Eleanor R. Schrems, have resulted in numerous shared publications. Lim's scholarship metrics include an h-index of 13, with 42 total publications and 491 total citations.
Metrics
- h-index: 13
- Publications: 41
- Citations: 494
Positions
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Postdoc 2022–presentUniversity of California Los Angeles Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research ORCID
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Research Assistant 2018–presentUniversity of Arkansas Human Health, Performance, and Recreation ORCID
Selected Publications
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Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females (2025)
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Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice (2025)
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Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice (2024)
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Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia (2023)
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The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males (2023)
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Development of skeletal muscle fibrosis in a rodent model of cancer cachexia (2023)
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MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16 (2023)
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Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia (2023)
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A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle (2022)
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The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from Males (2022)
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Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks (2022)
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Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes (2022)
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Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia (2022)
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PGC-1α overexpression is not sufficient to mitigate cancer cachexia in either male or female mice (2022)
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Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner (2022)
Federal Grants 2 $775,000 total
NSF
Co-PI
Oct 2025 - Aug 2027
SCC-CIVIC-FA Track A: Dynamic Modeling of River Ecosystem Stability
NSF
Co-PI
Oct 2024 - Jun 2025
Collaboration Network
Top Collaborators
Nicholas P. Greene
University of Arkansas at Fayetteville
28 shared publications
In database
- Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks
- Development and progression of cancer cachexia: Perspectives from bench to bedside
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
Showing 5 of 28 shared publications
Tyrone A. Washington
University of Arkansas at Fayetteville
25 shared publications
In database
- Development and progression of cancer cachexia: Perspectives from bench to bedside
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
Showing 5 of 25 shared publications
Megan E. Rosa‐Caldwell
Beth Israel Deaconess Medical Center
19 shared publications
In database
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Altering aspects of mitochondrial quality to improve musculoskeletal outcomes in disuse atrophy
Showing 5 of 19 shared publications
Francielly Morena da Silva
University of Arkansas at Fayetteville
14 shared publications
In database
- Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
Showing 5 of 14 shared publications
Eleanor R. Schrems
University of Arkansas at Fayetteville
12 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
Showing 5 of 12 shared publications
Wesley S. Haynie
University of Arkansas at Fayetteville
11 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Altering aspects of mitochondrial quality to improve musculoskeletal outcomes in disuse atrophy
- Comparative plasma proteomics in muscle atrophy during cancer‐cachexia and disuse: The search for atrokines
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
Showing 5 of 11 shared publications
Ana Regina Cabrera
University of Arkansas at Fayetteville
11 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
Showing 5 of 11 shared publications
Lisa T. Jansen
University of Arkansas at Fayetteville
10 shared publications
In database
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Altering aspects of mitochondrial quality to improve musculoskeletal outcomes in disuse atrophy
- Comparative plasma proteomics in muscle atrophy during cancer‐cachexia and disuse: The search for atrokines
Showing 5 of 10 shared publications
Kirsten R. Dunlap
University of Arkansas at Fayetteville (US)
8 shared publications
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Comparative plasma proteomics in muscle atrophy during cancer‐cachexia and disuse: The search for atrokines
- Neither autophagy nor exercise training mode affect exercise-induced beneficial adaptations in high fat-fed mice
- Neither Autophagy Inhibition Nor High Intensity Interval Training Alter Exercise Adaptations During High Fat Feeding
Showing 5 of 8 shared publications
Jacob L. Brown
University of Arkansas at Fayetteville (US)
8 shared publications
- Development and progression of cancer cachexia: Perspectives from bench to bedside
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- PGC-1α overexpression is not sufficient to mitigate cancer cachexia in either male or female mice
Showing 5 of 8 shared publications
Kevin A. Murach
University of Arkansas at Fayetteville
8 shared publications
In database
- Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks
- A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle
- The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from males
- Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice
- MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16
Showing 5 of 8 shared publications
David E. Lee
University of Arkansas at Fayetteville (US)
7 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-16
Showing 5 of 7 shared publications
Michael P. Wiggs
Baylor University (US)
7 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia
Showing 5 of 7 shared publications
J. William Deaver
Vanderbilt University (US)
6 shared publications
- Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia
Showing 5 of 6 shared publications
Landen W. Saling
University of Arkansas at Fayetteville
6 shared publications
In database
- Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice
- Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
- Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner
- Development of skeletal muscle fibrosis in a rodent model of cancer cachexia
- Differential Induction Of Regulators Of Protein Turnover During C26-induced Cancer Cachexia Between Biological Sexes
Showing 5 of 6 shared publications
Similar Researchers
Based on overlapping research topics
Eleanor R. Schrems
University of Arkansas at Fayetteville
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Francielly Morena da Silva
University of Arkansas at Fayetteville
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Calvin S. Peterson
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Ruqaiza Muhyudin
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University of Arkansas at Fayetteville
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