Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
L
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Lokesh Akana's research focuses on enhancing the effectiveness of cancer treatments, particularly in pancreatic and rectal cancers. His work investigates strategies to increase radiosensitivity, the susceptibility of tumor cells to radiation therapy. This includes exploring the inhibition of specific cellular targets, such as Cyclin-dependent kinase 1 (CDK1), and the role of epigenetic modifiers like SETD2. Akana has published on the potential of targeting these pathways to improve treatment outcomes, with several publications detailing preclinical validation in animal models. His collaborations include work with researchers at the University of Arkansas for Medical Sciences and the University of Arkansas at Little Rock. Akana's scholarship metrics include an h-index of 1 across 8 publications.
Metrics
- h-index: 1
- Publications: 8
- Citations: 6
Selected Publications
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Abstract A033: Targeting SETD2 in Combination with Radiotherapy in Rectal Cancer (2025)
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SETD2 Loss Predicts Response to Chemoradiotherapy in Rectal Cancer: Clinical Outcomes and Preclinical Validation in Orthotopic Models (2025)
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Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction (2025)
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Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1 (2024)
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Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1 (2024)
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Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer (2024)
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Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy (2023)
Collaboration Network
Top Collaborators
Adam R. Wolfe
University of Arkansas for Medical Sciences
7 shared publications
In database
- Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
- Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
Showing 5 of 7 shared publications
Henrique Rodrigues
University of Arkansas for Medical Sciences
4 shared publications
In database
- Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Abstract A033: Targeting SETD2 in Combination with Radiotherapy in Rectal Cancer
Saaimatul Huq
University of Arkansas for Medical Sciences
4 shared publications
In database
- Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
- Abstract A033: Targeting SETD2 in Combination with Radiotherapy in Rectal Cancer
H. Rodrigues
University of Arkansas for Medical Sciences
2 shared publications
In database
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
- SETD2 Loss Predicts Response to Chemoradiotherapy in Rectal Cancer: Clinical Outcomes and Preclinical Validation in Orthotopic Models
Oscar Zuniga
University of Arkansas for Medical Sciences
2 shared publications
In database
- Abstract A006: Targeting SETD2 in combination with radiotherapy in rectal cancer
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
Stetson Van Matre
University of Arkansas for Medical Sciences
2 shared publications
In database
- Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
Óscar Zúñiga
University of Arkansas for Medical Sciences
2 shared publications
In database
- Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1
- Abstract A011: Enhanced Radiosensitivity of Pancreatic Cancer Achieved through Inhibition of Cyclin-Dependent Kinase 1
A.Z. Kesaria
University of Arkansas for Medical Sciences (US)
1 shared publication
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
Eric U. Yee
University of Arkansas for Medical Sciences
1 shared publication
In database
- Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy
Daniel E. Eldridge
Medical University of South Carolina (US)
1 shared publication
- Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1
Henrique Rodrigues
University of Arkansas for Medical Sciences (US)
1 shared publication
- Enhanced radiosensitivity of pancreatic cancer achieved through inhibition of Cyclin-dependent kinase 1
Isabelle R. Miousse
University of Arkansas for Medical Sciences
1 shared publication
In database
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
Sarita Garg
University of Arkansas for Medical Sciences
1 shared publication
In database
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
Kimberly J. Krager
University of Arkansas for Medical Sciences
1 shared publication
In database
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
David N. Church
University of Arkansas for Medical Sciences
1 shared publication
In database
- Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
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