Eric U. Yee
Associate Professor
Also affiliated: Boston Children's Hospital (2013); Beth Israel Deaconess Medical Center (2012–2023); Harvard University (2012–2017); University of Oklahoma Medical Center (2017); University of Oklahoma Health Sciences Center (2017–2023); Stony Brook University (2020–2021); University of Colorado Denver (2010)
Pathology, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Eric U. Yee's research focuses on the mechanisms of disease, particularly in the context of gastrointestinal and pancreatic conditions. He has investigated how specific molecular pathways, such as those involving ZIP4 and ZO-1, contribute to pancreatic cancer progression. His work also explores the role of immune responses in inflammatory bowel diseases, including ulcerative colitis and autoimmune liver disease, examining how factors like CD39 impact T-cell function.
Yee has also contributed to the study of disease models, including the use of DBA/2N mice for systemic candidiasis and aspergillosis. His research has explored potential therapeutic strategies, such as the use of branched fatty acid esters of hydroxy fatty acids (FAHFAs) to protect against colitis by modulating gut immune responses.
His academic contributions include a substantial publication record, with 94 total publications and over 1,600 citations, reflecting a h-index of 23. He has collaborated with researchers from institutions including the University of Arkansas at Fayetteville and within the University of Arkansas for Medical Sciences, with shared publications with Felicia D. Allard, Mitchell R. McGill, Stefanie Kennon‐McGill, and Steven R. Post. Yee leads a research group and is recognized as a highly cited researcher.
Metrics
- h-index: 22
- Publications: 93
- Citations: 1,522
Positions
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Associate Professor 2021–presentUniversity of Arkansas for Medical Sciences Pathology, College of Medicine Institutional directory
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Associate Professor, Director of Surgical Pathology 2020–2021Stony Brook Medicine Pathology ORCID
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Assistant Professor 2017–2020University of Arkansas for Medical Sciences College of Medicine Pathology ORCID
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Staff Pathologist 2017–2020University of Arkansas for Medical Sciences Pathology ORCID
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Staff Pathologist 2016–2017University of Oklahoma Health Sciences Center Pathology ORCID
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Assistant Professor 2016–2017University of Oklahoma College of Medicine Pathology ORCID
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Associate Medical Director of Immunohistochemistry Laboratory 2014–2016Beth Israel Deaconess Medical Center Pathology ORCID
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Staff Pathologist 2012–2016Beth Israel Deaconess Medical Center Anatomic Pathology ORCID
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Instructor in Pathology 2012–2016Harvard Medical School Pathology ORCID
Selected Publications
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Neuroendocrine Differentiation in Mature Cystic Teratomas in Adults: A Case Report and Review of the Literature (2026)
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Repurposing Monensin and Its Derivatives as Immune-Modulatory Candidates for Metastatic Breast Cancer (Abstract ID: 231537) (2026)
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Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models (2025)
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Monensin and Its Analogs Exhibit Activity Against Breast Cancer Stem-Like Cells in an Organoid Model (2025)
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Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059) (2025)
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474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells (2025)
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Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract (2024)
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Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice (2024)
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Targeting Tri-Methyl-Histone H3 (Lys27) in Rectal Cancer: A Novel Strategy to Enhance Radiosensitivity and Predict Response to Neoadjuvant Therapy (2023)
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Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult (2023)
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Budesonide, an anti-inflammatory drug, exacerbate clostridioides difficile colitis in mice (2023)
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S2431 A Rare Case of Esophageal Kaposi Sarcoma Causing Dysphagia (2022)
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Predicting the Visual Attention of Pathologists Evaluating Whole Slide Images of Cancer (2022)
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Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult in mice (2022)
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Radiation Effects on Methamphetamine Pharmacokinetics and Pharmacodynamics in Rats (2022)
Collaboration Network
Top Collaborators
- Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations
- Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult
- Mucosal Biomarker of Innate Immune Activation Predicts Response to Vedolizumab in Crohn’s Disease
- Epithelial Cell Biomarkers Are Predictive of Response to Biologic Agents in Crohn’s Disease
- Intraobserver and Interobserver Variability in the Assessment of Dysplasia in Ampullary Mucosal Biopsies
Showing 5 of 11 shared publications
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations
- Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult
- Radiation Effects on Methamphetamine Pharmacokinetics and Pharmacodynamics in Rats
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
Showing 5 of 6 shared publications
- Mucosal Biomarker of Innate Immune Activation Predicts Response to Vedolizumab in Crohn’s Disease
- Epithelial Cell Biomarkers Are Predictive of Response to Biologic Agents in Crohn’s Disease
- Epithelial cell biomarkers are predictive of response to biologic agents in Crohn’s disease
- Rare Presentation of Neuroendocrine Carcinoma and Adenocarcinoma Occurring Independently in Same Segment of Colon
- 734 Colonic Biopsy Pyroptosis Predicts Clinical Response to Vedolizumab in Crohn's Disease
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations
- Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult in mice
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Dietary Methionine Supplementation Exacerbates Gastrointestinal Toxicity in a Mouse Model of Abdominal Irradiation
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
- Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059)
- Monensin and Its Analogs Exhibit Activity Against Breast Cancer Stem-Like Cells in an Organoid Model
- Repurposing Monensin and Its Derivatives as Immune-Modulatory Candidates for Metastatic Breast Cancer (Abstract ID: 231537)
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
- Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059)
- Monensin and Its Analogs Exhibit Activity Against Breast Cancer Stem-Like Cells in an Organoid Model
- Repurposing Monensin and Its Derivatives as Immune-Modulatory Candidates for Metastatic Breast Cancer (Abstract ID: 231537)
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
- Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059)
- Monensin and Its Analogs Exhibit Activity Against Breast Cancer Stem-Like Cells in an Organoid Model
- Repurposing Monensin and Its Derivatives as Immune-Modulatory Candidates for Metastatic Breast Cancer (Abstract ID: 231537)
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
- Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059)
- Monensin and Its Analogs Exhibit Activity Against Breast Cancer Stem-Like Cells in an Organoid Model
- Repurposing Monensin and Its Derivatives as Immune-Modulatory Candidates for Metastatic Breast Cancer (Abstract ID: 231537)
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
- Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059)
- Monensin and Its Analogs Exhibit Activity Against Breast Cancer Stem-Like Cells in an Organoid Model
- Repurposing Monensin and Its Derivatives as Immune-Modulatory Candidates for Metastatic Breast Cancer (Abstract ID: 231537)
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations
- Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult
- Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult in mice
- Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration
- Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract
- Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract
- Inter-strain variability in responses to a single administration of the cannabidiol-rich cannabis extract in mice
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