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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Katherine Wallis

Research Assistant

Also affiliated: University of California, Irvine (1980)

Graduate Student Researcher

5 h-index 20 pubs 160 cited

  • Humans
  • Melanoma
  • Gastrointestinal Microbiome
  • Bacteria
  • Female
  • Methionine
  • Sex Characteristics
  • Resveratrol
  • Antigen Presentation
  • Breast Neoplasms
  • Doxorubicin
  • Cardiotoxicity
  • Animals
  • Male
  • Mice, Inbred C57BL

Biography and Research Information

OverviewAI-generated summary

Katherine Wallis's research focuses on the intersection of diet, metabolism, and cancer treatment, particularly investigating the role of nutrient restriction in enhancing responses to immune checkpoint inhibitors. Her work has explored the impact of methionine depletion on tumor-bearing mice, demonstrating increased sensitivity to immunotherapies in colorectal cancer models. Wallis has also investigated the effects of caloric restriction mimetics and compounds like resveratrol on melanoma treatment, examining their influence on antigen presentation and immune responses. Her experimental approaches include cell culture, in vitro assays, and studies in animal models, involving techniques such as western blots, Seahorse assays, and tissue collection. Wallis has also processed clinical patient samples for research purposes and optimized tumor models. She has a publication record that includes studies on cell death mechanisms, immune checkpoint inhibitors, and melanoma treatment strategies.

Metrics

  • h-index: 5
  • Publications: 20
  • Citations: 160

Selected Publications

  • Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer (2026)
    Metabolomics DOI OpenAlex
  • Abstract 6545: Characterizing ATF6 activation-driven mechanisms improving ICB efficacy (2026)
    Cancer Research DOI OpenAlex
  • 685 EZH2 inhibition impairs CD8+ CAR-T cell persistence (2025)
    Regular and Young Investigator Award Abstracts DOI OpenAlex
  • 691 ATF6 activation promotes ICB response in melanoma (2025)
    Regular and Young Investigator Award Abstracts DOI OpenAlex
  • 762 CD28 costimulation induces PCK2 to support T cell effector function in metabolically hostile environments (2025)
    Regular and Young Investigator Award Abstracts DOI OpenAlex
  • 236 Manipulating the DNA damage response to combat T cell exhaustion and improve immunotherapy response (2025)
    Regular and Young Investigator Award Abstracts DOI OpenAlex
  • 538 ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response (2024)
    Regular and Young Investigator Award Abstracts DOI OpenAlex
  • 929 Proteomic analysis reveals differential modulation of the DNA damage response in exhausted T cells (2024)
    Regular and Young Investigator Award Abstracts DOI OpenAlex
  • 932 Defining the role for PCK2 in T-cell metabolic plasticity (2024)
    Regular and Young Investigator Award Abstracts DOI OpenAlex
  • Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients (2024)
    Cancer Research DOI OpenAlex
  • Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma (2023)
    Molecular Immunology 5 citations DOI OpenAlex
  • Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model (2023)
    Cancers 31 citations DOI OpenAlex
  • Increased response to immune checkpoint inhibitors with dietary methionine restriction (2023)
    bioRxiv (Cold Spring Harbor Laboratory) 7 citations DOI OpenAlex
  • Abstract P3-08-08: Establishment of a Breast Cancer Rat Model of Chemotherapy-Induced Cardiotoxicity (2023)
    Cancer Research DOI OpenAlex
  • Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction (2023)
    SSRN Electronic Journal 5 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

38 Collaborators 4 Institutions 1 Country

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