Pieter J. Koopmans Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Graduate Research Assistant
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Biography and Research Information
OverviewAI-generated summary
Pieter J. Koopmans investigates molecular and physiological adaptations in skeletal muscle, focusing on satellite cells, myonuclei, and the roles of microRNAs (miRNAs). His research explores how these components respond to stimuli such as exercise and disease states like cancer cachexia. Koopmans' work has examined the impact of specific miRNAs, including miR-16 and miR-1, on muscle gene expression, metabolic flexibility, and myogenic processes. He has also investigated the effects of interventions like exercise models in mice and senolytic compounds on muscle health and aging.
His recent publications include studies on the temporal molecular responses to resistance exercise in human skeletal muscle, implicating MYC as a regulator of muscle growth. Koopmans also studies the potential of mitochondrial antioxidants to attenuate muscle wasting in cancer models and the effects of senolytics on DNA methylation in aged muscle. His collaborations include work with Kevin A. Murach, Francielly Morena da Silva, and Nicholas P. Greene at the University of Arkansas at Fayetteville.
Metrics
- h-index: 6
- Publications: 17
- Citations: 83
Selected Publications
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The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice (2026)
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Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle (2025)
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The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus (2025)
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Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle (2025)
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Promoting mitochondrial fusion is protective against cancer-induced muscle detriments in males and females (2025)
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Corrigendum to “microRNA-1 regulates metabolic flexibility by programming skeletal muscle pyruvate metabolism” [Mol Metabol 98 (2025) 1–23/102182] (2025)
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microRNA-1 regulates metabolic flexibility by programming adult skeletal muscle pyruvate metabolism (2025)
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Global mitophagy inhibition via BNIP3 ablation is not sufficient to alleviate skeletal muscle impairments in male and female tumor-bearing mice (2025)
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Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice (2025)
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At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic ( <scp>BI01</scp> ) Administration on <scp>DNA</scp> Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle (2025)
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The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth (2024)
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Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice (2024)
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microRNA-1 Regulates Metabolic Flexibility in Skeletal Muscle via Pyruvate Metabolism (2024)
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The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates <i>MYC</i> as a Hypertrophic Regulator That is Sufficient for Growth (2024)
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Stuart has got the PoWeR! Skeletal muscle adaptations to a novel heavy progressive weighted wheel running exercise model in C57BL/6 mice (2023)
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