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Current · Arkansas
Last published
2025
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OpenAlex · ORCID
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2026-10-05
A
Azra Dad
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Research Participation Program/ ORISE Postdoctoral Fellow
Also affiliated: United States Food and Drug Administration (2017–2025); University of Illinois Urbana-Champaign (2013–2019); COMSATS University Islamabad (2013)
10 h-index
19 pubs
342 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Azra Dad is a postdoctoral fellow at the National Center for Toxicological Research (NCTR) through the Research Participation Program/ORISE. Her research focuses on genotoxicity assessment, particularly investigating the effects of chemical mutagens in animal models. Dad has published work examining the dose-response relationship of ethyl methanesulfonate-induced genotoxicity across different life stages and tissues in rats. Her research also explores background mutation frequencies in cell lines such as TK6 and L5178Y, with implications for error-corrected sequencing.
Further contributions include studies on *Pig-a* gene mutations in the bone marrow granulocytes of rats treated with procarbazine. Her scholarly output includes 19 publications with 327 citations and an h-index of 10. Dad collaborates with researchers at NCTR, including Javier R. Revollo, Robert H. Heflich, and Mason G. Pearce, with whom she shares multiple publications.
Metrics
- h-index: 10
- Publications: 19
- Citations: 342
Positions
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Research Participation Program/ ORISE Postdoctoral Fellow 2016–presentOak Ridge Institute for Science and Education Food and Drug Administration/ National Center for Toxicological Resaerch at the Division of Genetic and Molecular Toxicology”. ORCID
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Research Participation Program/ ORISE Postdoctoral Fellow publications 2017–2025National Center for Toxicological Research ORCID
Selected Publications
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Background Mutation Frequencies in TK6 and L5178Y Cells: Implications for Error‐Corrected Sequencing (2025)
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Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity (2021)
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Pig‐a gene mutations in bone marrow granulocytes of procarbazine‐treated F344 rats (2021)
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Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay (2020)
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CD59 ‐deficient bone marrow erythroid cells from rats treated with procarbazine and propyl‐nitrosourea have mutations in thePig‐agene (2020)
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Fungicide suppression of flight performance in the honeybee ( Apis mellifera ) and its amelioration by quercetin (2019)
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Pig-a mutations in bone marrow erythroblasts of rats treated with 7,12-dimethyl-benz[a]anthracene (2019)
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Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays (2018)
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Analysis of mutation in the rat Pig‐a assay: I) studies with bone marrow erythroid cells (2018)
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Analysis of mutation in the rat Pig‐a assay: II. Studies with bone marrow granulocytes (2018)
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Genome-wide mutation detection by interclonal genetic variation (2018)
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Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells (2017)
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Spectrum of benzo[ a ]pyrene-induced mutations in the Pig-a gene of L5178Y Tk +/− cells identified with next generation sequencing (2017)
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Chloramination of wastewater effluent: Toxicity and formation of disinfection byproducts (2017)
Collaboration Network
Top Collaborators
Javier R. Revollo
National Center for Toxicological Research
11 shared publications
In database
- Spectrum of benzo[ a ]pyrene-induced mutations in the Pig-a gene of L5178Y Tk +/− cells identified with next generation sequencing
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Genome-wide mutation detection by interclonal genetic variation
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
- Analysis of mutation in the rat Pig‐a assay: I) studies with bone marrow erythroid cells
Showing 5 of 11 shared publications
Mason G. Pearce
National Center for Toxicological Research
10 shared publications
In database
- Spectrum of benzo[ a ]pyrene-induced mutations in the Pig-a gene of L5178Y Tk +/− cells identified with next generation sequencing
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Genome-wide mutation detection by interclonal genetic variation
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
- Analysis of mutation in the rat Pig‐a assay: I) studies with bone marrow erythroid cells
Showing 5 of 10 shared publications
Vasily N. Dobrovolsky
National Center for Toxicological Research
10 shared publications
In database
- Spectrum of benzo[ a ]pyrene-induced mutations in the Pig-a gene of L5178Y Tk +/− cells identified with next generation sequencing
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Genome-wide mutation detection by interclonal genetic variation
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
- Analysis of mutation in the rat Pig‐a assay: I) studies with bone marrow erythroid cells
Showing 5 of 10 shared publications
Robert H. Heflich
National Center for Toxicological Research
7 shared publications
In database
- Spectrum of benzo[ a ]pyrene-induced mutations in the Pig-a gene of L5178Y Tk +/− cells identified with next generation sequencing
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
- Analysis of mutation in the rat Pig‐a assay: II. Studies with bone marrow granulocytes
- Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay
Showing 5 of 7 shared publications
Page B. McKinzie
National Center for Toxicological Research
4 shared publications
In database
- Spectrum of benzo[ a ]pyrene-induced mutations in the Pig-a gene of L5178Y Tk +/− cells identified with next generation sequencing
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
- Pig‐a gene mutations in bone marrow granulocytes of procarbazine‐treated F344 rats
Roberta A. Mittelstaedt
National Center for Toxicological Research
4 shared publications
In database
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
- Pig-a mutations in bone marrow erythroblasts of rats treated with 7,12-dimethyl-benz[a]anthracene
- CD59 ‐deficient bone marrow erythroid cells from rats treated with procarbazine and propyl‐nitrosourea have mutations in thePig‐agene
- Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity
Yiying Wang
National Center for Toxicological Research (US)
3 shared publications
- Spectrum of benzo[ a ]pyrene-induced mutations in the Pig-a gene of L5178Y Tk +/− cells identified with next generation sequencing
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
Timothy W. Robison
United States Food and Drug Administration (US)
3 shared publications
- Analysis of mutation in the rat Pig‐a assay: I) studies with bone marrow erythroid cells
- Pig-a mutations in bone marrow erythroblasts of rats treated with 7,12-dimethyl-benz[a]anthracene
- CD59 ‐deficient bone marrow erythroid cells from rats treated with procarbazine and propyl‐nitrosourea have mutations in thePig‐agene
Berran Yücesoy
United States Food and Drug Administration (US)
2 shared publications
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
Hans Rosenfeldt
United States Food and Drug Administration (US)
2 shared publications
- Establishing a novel Pig‐a gene mutation assay in L5178YTk+/− mouse lymphoma cells
- Evaluation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) mutagenicity using in vitro and in vivo Pig-a assays
Dayton M. Petibone
National Center for Toxicological Research
2 shared publications
In database
- Analysis of mutation in the rat Pig‐a assay: I) studies with bone marrow erythroid cells
- Analysis of mutation in the rat Pig‐a assay: II. Studies with bone marrow granulocytes
Julien Le Roux
AgroParisTech (FR)
1 shared publication
- Chloramination of wastewater effluent: Toxicity and formation of disinfection byproducts
Michael J. Plewa
University of Illinois Urbana-Champaign (US)
1 shared publication
- Chloramination of wastewater effluent: Toxicity and formation of disinfection byproducts
Elizabeth D. Wagner
University of Illinois Urbana-Champaign (US)
1 shared publication
- Chloramination of wastewater effluent: Toxicity and formation of disinfection byproducts
Maolida Nihemaiti
Curtin University (AU)
1 shared publication
- Chloramination of wastewater effluent: Toxicity and formation of disinfection byproducts
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