Christoph J. Mora
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Also affiliated: University of Arkansas Medical Center (2024–2025)
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Christoph Mora's research focuses on the immunological mechanisms underlying hypertension. His work investigates the role of specific immune cells, such as CD8+ T-lymphocytes, and signaling pathways, including the IFNγ-PDL1 axis, in the development and progression of hypertension, particularly in salt-sensitive models. He has explored how these immune components interact with kidney and heart tissues to contribute to the disease. Mora also examines the involvement of P2X7 receptor-mediated activation of T cells in promoting hypertension. His research has been published in peer-reviewed journals, and he has a notable record of collaboration with colleagues at the University of Arkansas for Medical Sciences, including Katherine Deck, Shengyu Mu, Yunping Guo, and Tonya Rafferty.
Metrics
- h-index: 5
- Publications: 35
- Citations: 114
Selected Publications
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Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031 (2026)
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Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853 (2026)
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Kidney Resident Memory CD8+ T cells drive the immortality of hypertension (2026)
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Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension (2026)
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Nanoencapsulated gamma-oryzanol enhances fibroblast proliferation, migration, and reduces oxidative stress in H2O2-induced cellular aging model (2025)
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IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287 (2025)
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P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289 (2025)
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Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288 (2025)
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Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension (2025)
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Uncovering immune pathways for therapeutic targeting of hypertension (2025)
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Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)
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Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction (2025)
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Establishment of resident memory T cells anchors hypertension in the kidney (2025)
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T Cells Drive Kidney Memory for Hypertension (2024)
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Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024)
Collaboration Network
Top Collaborators
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- IFN-γ Contributes to the Immune Mechanisms of Hypertension
- The link between immunity and hypertension in the kidney and heart
- Mitochondrial proton leak in cardiac aging
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
Showing 5 of 27 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- IFN-γ Contributes to the Immune Mechanisms of Hypertension
- The link between immunity and hypertension in the kidney and heart
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
Showing 5 of 21 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- IFN-γ Contributes to the Immune Mechanisms of Hypertension
- The link between immunity and hypertension in the kidney and heart
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
Showing 5 of 13 shared publications
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Uncovering immune pathways for therapeutic targeting of hypertension
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
Showing 5 of 13 shared publications
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- SS-31 Attenuates Doxorubicin-induced Cardiomyoblast H9C2 Cell Senescence
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
Showing 5 of 13 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The link between immunity and hypertension in the kidney and heart
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development
Showing 5 of 12 shared publications
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- The link between immunity and hypertension in the kidney and heart
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
Showing 5 of 12 shared publications
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- Establishment of resident memory T cells anchors hypertension in the kidney
Showing 5 of 8 shared publications
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288
- IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
Showing 5 of 8 shared publications
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853
- Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853
- Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031
- Mitochondrial proton leak in cardiac aging
- SS-31 Attenuates Doxorubicin-induced Cardiomyoblast H9C2 Cell Senescence
- Nanoencapsulated gamma-oryzanol enhances fibroblast proliferation, migration, and reduces oxidative stress in H2O2-induced cellular aging model
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION
- The IFNγ-PDL1 Pathway Enhances CD8T-DCT Interaction to Promote Hypertension
- P2X7 -Mediated Antigen-Independent Activation of CD8 + T Cells Promotes Salt-Sensitive Hypertension
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