Match tier
Likely match
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
K
Kimberly J. Krager
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
High Impact
Researcher
Also affiliated: University of Iowa (2003–2015); Arkansas Children's Hospital (2017); Nebraska Medical Center (2023); Winthrop Rockefeller Foundation (2015); Radiation Oncology Associates (2004); Iowa City Public Library (2004); Pharmaceutical Biotechnology (Czechia) (2018–2024); Arkansas Department of Health (2018); University of Nebraska Medical Center (2023)
Faculty Researcher
21 h-index
73 pubs
2,949 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Kimberly J. Krager investigates the molecular mechanisms underlying bone loss, particularly in the context of aging and estrogen deficiency. Her research has explored the role of mitochondrial Sirtuin 3 (Sirt3) in age-related bone loss and bone loss due to estrogen deficiency. Krager has also studied the impact of transferrin receptor 1-mediated iron uptake on bone mass, examining its effects via osteoclast mitochondria and cytoskeleton. Her work has extended to the effects of ionizing radiation on bone health, specifically in young adult male mice, where she observed activation of mitochondrial function in osteoclasts leading to bone loss. Further research has examined simulated galactic cosmic rays' impact on osteoclast mitochondrial metabolism, osteoclastogenesis, and trabecular bone loss.
Beyond bone health, Krager's research has touched upon radiation-induced heart disease, investigating the role of Toll-like receptor 4 (TLR4). She has also examined the sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in various mouse tissues, including the heart, small intestine, and skin. Additionally, her work has included investigating the mechanism of parthenolide-induced ferroptosis in hepatocellular carcinoma cells.
Krager's scholarship metrics include an h-index of 21, with 73 total publications and 2,888 total citations. She is recognized as a highly cited researcher. Her key collaborators include Nükhet Aykin‐Burns, Francesca V. LoBianco, Ha‐Neui Kim, and Marjan Boerma, with whom she has multiple shared publications.
Metrics
- h-index: 21
- Publications: 73
- Citations: 2,949
Selected Publications
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Mitochondrial-targeted SS-31 peptide attenuates radiation-induced cardiomyocyte senescence (2026)
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Assessing Pain Linked to High Metabolic and Glycolytic Shift in Neurofibromatosis Type 1 (NF1) Patients by Using a Bioenergetic Biomarker: A Pilot Study (2026)
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Beneficial effects of an indole derivative melatonin analogue in estrogen receptor positive breast cancer (2026)
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SIRT3–IDH2 axis is a target of dietary fructose: implication of IDH2 as a key player in dietary carcinogen toxicity in mice colon (2025)
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Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025)
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Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction (2025)
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SIRT3-IDH2 axis is a target of dietary fructose: implication of IDH2 as a key player in dietary carcinogen toxicity in mice colon (2025)
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Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects (2023)
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TLR4—A Pertinent Player in Radiation-Induced Heart Disease? (2023)
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Abstract No. 106 Where are Women in Academic Interventional Radiology? (2023)
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Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)
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Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart (2023)
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Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)
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Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)
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Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice (2022)
Collaboration Network
Top Collaborators
Nükhet Aykin‐Burns
University of Arkansas for Medical Sciences
19 shared publications
In database
- Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
Showing 5 of 19 shared publications
Francesca V. LoBianco
University of Arkansas for Medical Sciences
6 shared publications
In database
- Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells
- Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model
- Abstract No. 584 Parthenolide induces thiol oxidation inducing ferroptosis in human hepatocellular carcinoma cells
- Overcoming the Restricted Therapy Options and Monitoring Challenges in Metastatic Breast Cancer
- Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model
Showing 5 of 6 shared publications
Ha‐Neui Kim
Central Arkansas Veterans Healthcare System
5 shared publications
In database
- Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
- Hem1 promotes osteoclast fusion and bone resorption in mice
Marjan Boerma
Winthrop Rockefeller Foundation
5 shared publications
In database
- TLR4—A Pertinent Player in Radiation-Induced Heart Disease?
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Small animal models of localized heart irradiation
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
- Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models
Wen Ling
University of Arkansas for Medical Sciences
4 shared publications
In database
- Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
Kimberly Richardson
University of Arkansas for Medical Sciences (US)
4 shared publications
- Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency
- Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice
- Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice
- Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
Vijayalakshmi Sridharan
University of Arkansas for Medical Sciences
4 shared publications
In database
- TLR4—A Pertinent Player in Radiation-Induced Heart Disease?
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Small animal models of localized heart irradiation
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
Aaron Warren
University of Arkansas for Medical Sciences
3 shared publications
In database
- Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency
- Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
- Hem1 promotes osteoclast fusion and bone resorption in mice
Maria Almeida
University of Arkansas for Medical Sciences
3 shared publications
In database
- Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency
- Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice
- Hem1 promotes osteoclast fusion and bone resorption in mice
Bhaba Krishna Das
Southern California Institute for Research and Education (US)
3 shared publications
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Toshifumi Fujiwara
Kyushu University Hospital (JP)
3 shared publications
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Renny S. Lan
University of Arkansas for Medical Sciences
3 shared publications
In database
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Samuel G. Mackintosh
University of Arkansas for Medical Sciences
3 shared publications
In database
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Ricky D. Edmondson
University of Arkansas for Medical Sciences
3 shared publications
In database
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Michael L. Jennings
University of Arkansas for Medical Sciences
3 shared publications
In database
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
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