Nükhet Aykin‐Burns Source Confirmed

OverviewAI-generated summary

Nükhet Aykin‐Burns' research focuses on understanding the molecular mechanisms underlying bone loss and the impact of various factors, including aging, estrogen deficiency, and ionizing radiation, on bone metabolism. Her work investigates the role of specific cellular components, such as transferrin receptor 1 and mitochondrial Sirt3, in regulating bone mass. She has explored how osteoclast mitochondria and cytoskeleton are influenced by iron uptake and how simulated galactic cosmic rays can alter mitochondrial metabolism in osteoclasts, leading to bone loss.

Further research by Aykin‐Burns examines the effects of chemotherapy-induced oxidative stress on the ovary and explores potential interventions. She also investigates the mechanisms of ferroptosis in hepatocellular carcinoma cells, specifically the role of thiol oxidation. Additionally, her publications address the role of microRNAs in viral infections, such as SARS-CoV-2, and the protective effects of phytochemicals like curcumin against acrolein-induced apoptosis in alveolar epithelial cells.

Aykin‐Burns leads a research group and collaborates with several colleagues at the University of Arkansas for Medical Sciences, including Kimberly J. Krager, Francesca V. LoBianco, Ha‐Neui Kim, and Brian Koss. She has published 111 papers, accumulating over 7,254 citations, and holds an h-index of 36. Her work has been recognized with a high-impact researcher designation.

Metrics

• h-index: 36
• Publications: 111
• Citations: 7,254